Table 5 Univariate analysis of the influence of the expression of proteins related to the ATX–LPA axis in thyroid papillary cancer on disease-free and overall survival by the log-rank test
From: Expression of proteins related to autotaxin–lysophosphatidate signaling in thyroid tumors
| Parameter | Number of patients/recurrence/death | Disease-free survival | Overall survival | ||
|---|---|---|---|---|---|
| Mean survival (95% CI) months | p-value | Mean survival (95% CI) months | p-value | ||
| ATX | 0.894 | 0.050 | |||
| Negative | 220/12/8 | 106 (103–109) | 109 (107–111) | ||
| Positive | 118/6/10 | 104 (101–108) | 102 (98–106) | ||
| LPA1 | 0.670 | 0.014 | |||
| Negative | 169/10/4 | 106 (103–109) | 110 (109–112) | ||
| Positive | 169/8/14 | 107 (104–110) | 105 (101–108) | ||
| LPA1 (S) | 0.156 | 0.909 | |||
| Negative | 323/16/17 | 107 (105–109) | 108 (106–109) | ||
| Positive | 15/2/1 | 96 (79–113) | 102 (89–116) | ||
| LPA2 | 0.947 | 0.316 | |||
| Negative | 191/10/8 | 107 (104–110) | 108 (106–111) | ||
| Positive | 147/8/10 | 106 (103–110) | 106 (103–110) | ||
| LPA3 | 0.209 | 0.204 | |||
| Negative | 56/1/1 | 108 (104–111) | 108 (106–111) | ||
| Positive | 282/17/17 | 106 (103–109) | 107 (105–109) | ||
