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Table 5 Univariate analysis of the influence of the expression of proteins related to the ATX–LPA axis in thyroid papillary cancer on disease-free and overall survival by the log-rank test

From: Expression of proteins related to autotaxin–lysophosphatidate signaling in thyroid tumors

Parameter Number of patients/recurrence/death Disease-free survival Overall survival
Mean survival (95% CI) months p-value Mean survival (95% CI) months p-value
ATX 0.894   0.050
 Negative 220/12/8 106 (103–109)   109 (107–111)  
 Positive 118/6/10 104 (101–108)   102 (98–106)  
LPA1 0.670   0.014
 Negative 169/10/4 106 (103–109)   110 (109–112)  
 Positive 169/8/14 107 (104–110)   105 (101–108)  
LPA1 (S) 0.156   0.909
 Negative 323/16/17 107 (105–109)   108 (106–109)  
 Positive 15/2/1 96 (79–113)   102 (89–116)  
LPA2 0.947   0.316
 Negative 191/10/8 107 (104–110)   108 (106–111)  
 Positive 147/8/10 106 (103–110)   106 (103–110)  
LPA3 0.209   0.204
 Negative 56/1/1 108 (104–111)   108 (106–111)  
 Positive 282/17/17 106 (103–109)   107 (105–109)  
  1. Italic values represent significance of p-value (p < 0.05)