From: Expression of proteins related to autotaxin–lysophosphatidate signaling in thyroid tumors
Parameters | Total n = 545 (%) | PTC n = 338 (%) | FC n = 111 (%) | MC n = 69 (%) | PDC n = 23 (%) | AC n = 4 (%) | p-value |
---|---|---|---|---|---|---|---|
ATX | < 0.001 | ||||||
Negative | 368 (67.5) | 220 (65.1) | 102 (91.9) | 22 (31.9) | 21 (91.3) | 3 (75.0) | |
Positive | 177 (32.5) | 118 (34.9) | 9 (8.1) | 47 (68.1) | 2 (8.7) | 1 (25.0) | |
LPA1 | < 0.001 | ||||||
Negative | 292 (53.6) | 169 (50.0) | 73 (65.8) | 44 (63.8) | 5 (21.7) | 1 (25.0) | |
Positive | 253 (46.4) | 169 (50.0) | 38 (34.2) | 25 (36.2) | 18 (78.3) | 3 (75.0) | |
LPA1 (S) | 0.051 | ||||||
Negative | 530 (97.2) | 323 (95.6) | 111 (100.0) | 69 (100.0) | 23 (100.0) | 4 (100.0) | |
Positive | 15 (2.8) | 15 (4.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
LPA2 | < 0.001 | ||||||
Negative | 365 (67.0) | 191 (56.5) | 85 (76.6) | 69 (100.0) | 16 (69.6) | 4 (100.0) | |
Positive | 180 (33.0) | 147 (43.5) | 26 (23.4) | 0 (0.0) | 7 (30.4) | 0 (0.0) | |
LPA3 | < 0.001 | ||||||
Negative | 189 (34.7) | 56 (16.6) | 52 (46.8) | 67 (97.1) | 10 (43.5) | 4 (100.0) | |
Positive | 356 (65.3) | 282 (83.4) | 59 (53.2) | 2 (2.9) | 13 (56.5) | 0 (0.0) |