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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: A novel CD147 inhibitor, SP-8356, reduces neointimal hyperplasia and arterial stiffness in a rat model of partial carotid artery ligation

Fig. 1

Discovery and activity of SP-8356. a Screening strategy. b Structure of SP-8356. c Representative image and quantitative analysis of CD147 dimerization. Data are presented as the mean ± standard deviation (SD) of three independent experiments. *p < 0.05 vs. vehicle. d Surface plasmon resonance (SPR) assay of anti-CD147 antibody, AC-73, and SP-8356 with CD147

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