Fig. 2

Administration of losartan lowers diastolic blood pressure and attenuates myocardial dysfunction in tail-suspended mice. Tail-suspended mice were given losartan or vehicle in drinking water for 28 days. a, b Blood pressure was measured in mice. c, d Ejection fraction (EF)% and fraction shortening (FS)%. Data are mean ± SD, n = 6 in each group. *P < 0.05 vs. Sham + Vehicle and ^†P < 0.05 vs. TS + Vehicle