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Table 1 Expression pattern of GJB2 and TMPRSS3 genes

From: Overinterpretation of high throughput sequencing data in medical genetics: first evidence against TMPRSS3/GJB2 digenic inheritance of hearing loss

Inner ear structure GJB2 expression TMPRSS3 expression
Rodents [22] Human [9] Rodents [23, 24] Human [10]
Inner hair cells + +
Outer hair cells ± +
Interdental cells + N/A + N/A
Spiral limbus + N/A N/A
Inner sulcus cells + N/A + N/A
Inner pillar cells + +
Outer pillar cells + + +
Deiter’s cells + + + +
Hensen cells + + + N/A
Claudius cells + + + N/A
External sulcus cells + N/A + N/A
Stria vascularis + + + ±
Spiral ligament + + N/A
Spiral ganglion + + ±
  1. −, no expression detected; +, detected expression; ±, inconsistent expression data; N/A, no data available