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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: B7-H3 participates in human salivary gland epithelial cells apoptosis through NF-κB pathway in primary Sjögren’s syndrome

Fig. 4

The impact of B7-H3 expression on HSGE cells apoptosis. a The epithelial characteristic of cultured HSGE cells was verified routinely by morphology. b HSGE cells labeled by CK-8 (95.23%) (right histogram) and blank control (left histogram). c By flow cytometry, we tested the effects of B7-H3 in primary HSGE cells on apoptosis. d The total apoptosis is the sum of early and late apoptosis. Quantitative results of the total percentages of apoptotic primary cells in the healthy control group and pSS patient group. *P < 0.05 vs. the healthy controls. e The cells were transfected for 48 h before detection. The apoptosis rates of control, upregulated-B7-H3 or downregulted-B7-H3, NC of HSGE cell lines were analyzed. f Quantitative results of the total percentages of apoptotic cells in the control, upregulated-B7-H3, downregulted-B7-H3, NC group. *P < 0.05 vs. the NC group

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