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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: First-in-human study of TK-positive oncolytic vaccinia virus delivered by adipose stromal vascular fraction cells

Fig. 3

Kaplan-Meier plots showing the relative survival of a total of 25 patients (23 patients with solid tumors and 2 patients with AML). a Patient survival relative to the presence of persistent vaccinia virus DNA in the blood for 1 week to 3 months post treatment. Median survival: without persistent VV, 5 months, (n = 14) vs. with persistent VV, 10 months (n = 11). b Patient survival relative to reported presence of skin rashes. Median survival: without skin rashes, 5 months (n = 17) vs. with skin rashes, undefined (n = 8). c Patient survival relative to the presence of both skin rashes and persistent vaccinia virus DNA in the blood. Median survival: with either or none, 5 months, (n = 20) vs. with both, undefined (n = 5). Vertical tick marks indicate patients who dropped from the study or were censored from analysis after switching to alternative cancer treatments

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