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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Kinetics of MSC-based enzyme therapy for immunoregulation

Fig. 5

ELISA quantification of IL-1β secretion from monocytes when co-stimulated with LPS and ATP. a After culturing monocytes with or without MSCs in transwell inserts during the stimulation period, samples were analyzed with IL-1beta ELISA. b The cocultured groups released significantly less IL-1β than monocytes alone (n = 5 per group) where p < 0.10 for the 500 and 1000 nmol ATP groups. At these doses, the monocyte only secretion was significantly higher than the control, compared to 1500 nmol which was too high to elicit IL-1 β secretion

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