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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Mesenchymal stem cells promote type 2 macrophage polarization to ameliorate the myocardial injury caused by diabetic cardiomyopathy

Fig. 3

MSCs improved cardiac function, blood glucose and lipid metabolism in DCM rats. MSCs were infused 4 times, and cardiac function was measured by echocardiography (a) at 20 weeks. Fasting blood glucose (b) was assessed throughout the MSC infusion process. Intraperitoneal glucose tolerance testing (c), fasting serum insulin (d) and the insulin sensitivity index (e) were used to evaluate glucose metabolism. Blood total cholesterol (f) and blood triglycerides (g) were also analyzed to assess lipid metabolism at 19 weeks. n = 3–6 per group for echocardiographic assessment, n = 5–8 per group for hematological assessment, ** P < 0.01 vs. normal group, ## P < 0.01 vs. DCM group

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