Fig. 1

Heatmap showing clustering of genetic variants and associated traits. Each cell corresponds to the result of a linear or logistic regression. A blue cell denotes a reduction of the quantitative trait or disease risk, red denotes increase. The color intensity shows the association strength (absolute value of the t statistic). With few exceptions, the SNPs cluster according to the pGC vs sGC pathways. For the traits there is a cluster with blood pressure traits and one with anthropometric traits. There are also some interesting sub-clusters, including one containing myocardial infarction and atherosclerosis