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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Meeting abstracts from the 9th International Conference on cGMP: Generators, Effectors and Therapeutic Implications

Fig. 1

Crystal structure of the PKG Ib holoenzyme complex. The domain organization is shown at the top and the structure of the PKG Ib holoenzyme complex below. The trans-inhibiting dimer is shown with one monomer with surface and the other in cartoon representation. The autoinhibitor (AI) sequence and the interlinking helix between CNB-A and B are colored in red. CNB-A is colored in teal, CNB-B in cyan and PBCs in yellow. The small and large lobes are colored in black and tan respectively. The C-terminal loop is shown in red. The disordered regions between the R and C-domain are shown in dotted lines

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Journal of Translational Medicine

ISSN: 1479-5876

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