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Table 3 Estimation efficiency (mean ± half-width of 95% CI) of the optimal design and the benchmark design for HIV prevalence estimation (with an actual prevalence rate of \(p=0.044\))

From: A methodology for deriving the sensitivity of pooled testing, based on viral load progression and pooling dilution

Performance metric

Optimal design

Benchmark design

Pool design

\(n^* = 37, s^* = 17\)

\(n^* = 17, s^* = 33\)

\({\hat{p}}\) (MLE)

0.05204 ± 0.00036

0.03041 ± 0.00029

MSE \((\times 10^4)\)

3.95 ± 0.11

4.00 ± 0.08

rBias (%)

18.26 ± 0.52

30.88 ± 0.48