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Table 1 The basic information of 10 PDX models

From: Frequent genetic aberrations in the cell cycle related genes in mucosal melanoma indicate the potential for targeted therapy

Code Gender Age Ulceration Anatomic site Stage CDK4 CCND1 P16 INK4a KIT BRAF NRAS
PDX-001 M 49 Yes 1 IV Normal Normal Normal WT WT WT
PDX-002 M 57 Yes 4 IV Normal Normal Normal W557R WT WT
PDX-003 F 78 Yes 5 II Gain Gain Loss WT WT WT
PDX-004 F 43 Yes 5 III Gain Gain Loss L576P WT WT
PDX-005 F 57 Yes 5 II Gain Gain Loss WT WT WT
PDX-006 M 58 Yes 3 I Gain Gain Loss WT WT WT
PDX-007 F 71 Yes 2 II Gain Gain Normal WT WT WT
PDX-008 F 65 No 1 II Gain Gain Normal WT WT G12C
PDX-009 F 69 Yes 1 II Normal Gain Loss WT WT Q61L
PDX-010 M 55 Yes 2 II Normal Gain Normal WT WT WT
  1. F female, M male, WT wild type
  2. a: Anatomic site: 1 = nasopharynx; 2 = oral cavities; 3 = esophagus; 4 = anorectum; 5 = genitourinary