Table 2 KEGG pathway analysis of 38 overlapping genes in si-CSTF2 cell line

uc001dlw.2

SH3-domain GRB2-like endophilin B1

hsa04144:Endocytosis

uc001kta.2

Beta-transducin repeat containing

hsa04114:Oocyte meiosis, hsa04120:Ubiquitin mediated proteolysis, hsa04310:Wnt signaling pathway, hsa04340:Hedgehog signaling pathway

uc002pew.2

Calmodulin 3 (phosphorylase kinase, delta); calmodulin 2 (phosphorylase kinase, delta); calmodulin 1 (phosphorylase kinase, delta)

hsa04020:Calcium signaling pathway, hsa04070:Phosphatidylinositol signaling system, hsa04114:Oocyte meiosis, hsa04270:Vascular smooth muscle contraction, hsa04720:Long-term potentiation, hsa04722:Neurotrophin signaling pathway, hsa04740:Olfactory transduction, hsa04910:Insulin signaling pathway, hsa04912:GnRH signaling pathway, hsa04916:Melanogenesis, hsa05010:Alzheimer’s disease, hsa05214:Glioma

uc003iev.1

Fibroblast growth factor 2 (basic)

hsa04010:MAPK signaling pathway, hsa04810:Regulation of actin cytoskeleton, hsa05200:Pathways in cancer, hsa05218:Melanoma

uc002tbc.2

Mitogen-activated protein kinase kinase kinase kinase 4

hsa04010:MAPK signaling pathway

uc003hzp.2

Phospholipase A2, group XIIA

hsa00564:Glycerophospholipid metabolism, hsa00565:Ether lipid metabolism, hsa00590:Arachidonic acid metabolism, hsa00591:Linoleic acid metabolism, hsa00592:alpha-Linolenic acid metabolism, hsa04010:MAPK signaling pathway, hsa04270:Vascular smooth muscle contraction, hsa04370:VEGF signaling pathway, hsa04664:Fc epsilon RI signaling pathway, hsa04730:Long-term depression, hsa04912:GnRH signaling pathway

uc003hbs.1

Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase

hsa00230:Purine metabolism

uc002fuw.3

Platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45 kDa)

hsa00565:Ether lipid metabolism

uc002jhg.2

Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)

hsa04210:Apoptosis, hsa04910:Insulin signaling pathway,

uc004czg.3

Pyruvate dehydrogenase (lipoamide) alpha 1

hsa00010:Glycolysis/Gluconeogenesis, hsa00020:Citrate cycle (TCA cycle), hsa00290:Valine, leucine and isoleucine biosynthesis, hsa00620:Pyruvate metabolism, hsa00650:Butanoate metabolism,

uc001xbo.2

Suppressor of cytokine signaling 4

hsa04630:Jak-STAT signaling pathway, hsa04910:Insulin signaling pathway, hsa04930:Type II diabetes mellitus