Fig. 4

CSTF2 regulates 3′UTR shortening of genes in NSCLC cell. a siRNA transduction reduces the mRNA (left) and protein (right) levels of CSTF2 gene in H460 cells. b Comparison of distribution pattern for poly(A) signals in data sets of clinical samples and H460 cells. c Profiling of 60 genes with elongated 3′UTR length in H460 cells with knocking-down of CSTF2 expression. d Profiling of 18 genes with shortened 3′UTR length in H460 cells with knocking-down of CSTF2 expression. e Venn diagram for comparison between overlapped genes detected in data sets of H460 cells and clinical samples