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Table 3 Correlation of Kyn, Trp and Kyn/Trp ratio with the continuous variables age, ER, PgR, Ki67 and size

From: Tryptophan catabolism increases in breast cancer patients compared to healthy controls without affecting the cancer outcome or response to chemotherapy

 

Kyn

Trp

Ratio

Correlation coefficient

95% CI

p value

Correlation coefficient

95% CI

p value

Correlation coefficient

95% CI

p value

Age (years)

0.295

0.196 to 0.389

< 0.0001***

0.028

− 0.078 to 0.133‏

0.610

0.300

0.200 to 0.393

< 0.0001***

ER (%)

0.010

− 0.129 to 0.148

0.890

0.146

0.008 to 0.279

0.039*

− 0.103

− 0.239 to 0.036

0.145

PgR (%)

− 0.074

− 0.211 to 0.065

0.297

0.116

− 0.023 to 0.250

0.103

 0.184

 0.315 to − 0.046

0.009**

Ki67 (%)

− 0.036

− 0.173 to 0.103

0.614

− 0.108

− 0.243 to 0.031

0.128

0.045

− 0.94 to 0.183

0.523

Size (mm)

0.003

− 0.137 to 0.142

0.968

 0.170

 0.302 to − 0.031

0.017*

0.119

− 0.021 to 0.254

0.096

  1. The correlation was calculated with the Spearman test. The correlation coefficient, 95% CI and p value are reported in the table. The significant correlations are reported in italics
  2. CI confidence interval, ER estrogen receptor, PgR progesterone receptor