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Table 1 Clinical parameters of the animals

From: Advantages of prophylactic versus conventionally scheduled heart failure therapy in an experimental model of doxorubicin-induced cardiomyopathy

  CON (n = 7) D-CON (n = 7) PRE (n = 8) POST (n = 7)
Day 0 Day 74 Day 0 Day 74 Day 0 Day 74 Day 0 Day 74
BW (g) 309.29 ± 5.25^ 481.71 ± 14.37+§^# 333.43 ± 20.42 328.29 ± 10.91* 331.38 ± 10.86 342.25 ± 49.7* 339.71 ± 10.04* 311.71 ± 22.85*
tBMI (kg/m2) 157 ± 3.57+§^ 248.87 ± 8.74+§^# 194.78 ± 18.392* 189.9 ± 9.71* 187.91 ± 10.62* 189.72 ± 15.98* 206.45 ± 11.16* 190.52 ± 7.88*
  CON (n = 7) D-CON + POST (n = 16) PRE (n = 5–8)
Day 0 Day 7 Day 39 Day 0 Day 7 Day 39 Day 0 Day 7 Day 39
SBP (mmHg) 123.31 ± 3.05§ 134.51 ± 7.85§ 132.77 ± 8.11 132.61 ± 3.27§ 136.11 ± 2.47§ 145.91 ± 5.54§# 149.73 ± 4.98*+ 112.63 ± 4.3*+# 115.44 ± 5.19+#
DBP (mmHg) 92.23 ± 2.49§ 104.91 ± 7.35§# 103.34 ± 6.34 102.41 ± 3.23§ 103.64 ± 3.01§ 110.34 ± 4.39§ 116.75 ± 7.06*+ 83.3 ± 3.79*+# 85.24 ± 5.77+#
HR (1/min) 418.31 ± 7.27§ 419.2 ± 13.05§ 405.51 ± 11.18 430.86 ± 11.73 435.75 ± 12.98§ 464.06 ± 19.36*§ 451.25 ± 11.81* 380.33 ± 10.41*+# 347.24 ± 6.59*+#
  1. BW body weight, DBP diastolic blood pressure, HR heart rate, SBP systolic blood pressure, tBMI body mass indexed for tibia length, n number of animals per group (5 measurements per animal, except for single body weight and tBMI measurements)
  2. * p ≤ 0.05 vs. CON; + p ≤ 0.05 vs. D-CON/D-CON + POST; § p ≤ 0.05 vs. PRE; ^ p ≤ 0.05 vs. POST; # p ≤ 0.05 vs. day 0