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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: Advantages of prophylactic versus conventionally scheduled heart failure therapy in an experimental model of doxorubicin-induced cardiomyopathy

Fig. 8

Biochemical measurements of proteins. A significantly decreased level of PGC1α was detected in the DOX-treated animals, irrespective of any treatment applied (a). A non-significant increase of P-ACC/ACC ratios was observed in the D-CON group compared to that in CON (b). A non-significant increase in the P-TnI was seen in the D-CON group compared to that in PRE (c). ACC acetyl coenzyme A carboxylase, AU optical density in arbitrary units, P-ACC phosphorylated ACC, PGC1α peroxisome proliferator-activated receptor-gamma coactivator 1 alpha, P-TnI phosphorylated troponin I, RI relative intensity. n  number of animals per group; Statistics: Wilcoxon’s rank-sum test; numbers are p values; NS: non-significant

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