Animal to human translation: a systematic scoping review of reported concordance rates

Table 1 Diagnostic statistics with binary definitions of translational success.

	Human test
	Positive (HP)	Negative (HN)
Animal test
Positive (AP)	TP	FP
Negative (AN)	FN	TN
Sensitivity = TP/HP
Specificity = TN/HN
Positive predictive value (PPV) = TP/AP
Negative predictive value (NPV) = TN/AN
Accuracy = (TP + TN)/(TP + FP + FN + TN)

AN animal negative, AP animal positive, FN false negative, FP false positive, HN human negative, HP human positive, TN true negative, TP true positive

ISSN: 1479-5876