TY - JOUR AU - Sethi, G. AU - Sung, B. AU - Kunnumakkara, A. B. AU - Aggarwal, B. B. PY - 2009 DA - 2009// TI - Targeting TNF for treatment of cancer and autoimmunity JO - Adv Exp Med Biol VL - 647 UR - https://doi.org/10.1007/978-0-387-89520-8_3 DO - 10.1007/978-0-387-89520-8_3 ID - Sethi2009 ER - TY - JOUR AU - Idriss, H. T. AU - Naismith, J. H. PY - 2000 DA - 2000// TI - TNF alpha and the TNF receptor superfamily: structure-function relationship (s) JO - Microsc Res Tech VL - 50 UR - https://doi.org/3.0.CO;2-H DO - 3.0.CO;2-H ID - Idriss2000 ER - TY - JOUR AU - Caminero, A. AU - Comabella, M. AU - Montalban, X. PY - 2011 DA - 2011// TI - Tumor necrosis factor alpha (TNF-alpha), anti-TNF-alpha and demyelination revisited: an ongoing story JO - J Neuroimmunol VL - 234 UR - https://doi.org/10.1016/j.jneuroim.2011.03.004 DO - 10.1016/j.jneuroim.2011.03.004 ID - Caminero2011 ER - TY - JOUR AU - Rodrigues, E. B. AU - Farah, M. E. AU - Maia, M. AU - Penha, F. M. AU - Regatieri, C. AU - Melo, G. B. PY - 2009 DA - 2009// TI - Therapeutic monoclonal antibodies in ophthalmology JO - Prog Retin Eye Res. VL - 28 UR - https://doi.org/10.1016/j.preteyeres.2008.11.005 DO - 10.1016/j.preteyeres.2008.11.005 ID - Rodrigues2009 ER - TY - JOUR AU - Derevjanik, N. L. AU - Vinores, S. A. AU - Xiao, W. H. AU - Mori, K. AU - Turon, T. AU - Hudish, T. PY - 2002 DA - 2002// TI - Quantitative assessment of the integrity of the blood-retinal barrier in mice JO - Invest Ophthalmol Vis Sci VL - 43 ID - Derevjanik2002 ER - TY - JOUR AU - Prada, J. AU - Noelle, B. AU - Baatz, H. AU - Hartmann, C. AU - Pleyer, U. PY - 2003 DA - 2003// TI - Tumour necrosis factor alpha and interleukin 6 gene expression in keratocytes from patients with rheumatoid corneal ulcerations JO - Br J Ophthalmol VL - 87 UR - https://doi.org/10.1136/bjo.87.5.548 DO - 10.1136/bjo.87.5.548 ID - Prada2003 ER - TY - JOUR AU - Theodossiadis, P. G. AU - Markomichelakis, N. N. AU - Sfikakis, P. P. PY - 2007 DA - 2007// TI - Tumor necrosis factor antagonists: preliminary evidence for an emerging approach in the treatment of ocular inflammation JO - Retina VL - 27 UR - https://doi.org/10.1097/MAJ.0b013e3180318fbc DO - 10.1097/MAJ.0b013e3180318fbc ID - Theodossiadis2007 ER - TY - JOUR AU - Berger, S. AU - Savitz, S. I. AU - Nijhawan, S. AU - Singh, M. AU - David, J. AU - Rosenbaum, P. S. PY - 2008 DA - 2008// TI - Deleterious role of TNF-alpha in retinal ischemia-reperfusion injury JO - Invest Ophthalmol Vis Sci VL - 49 UR - https://doi.org/10.1167/iovs.07-0817 DO - 10.1167/iovs.07-0817 ID - Berger2008 ER - TY - JOUR AU - Nagineni, C. N. AU - Kommineni, V. K. AU - William, A. AU - Detrick, B. AU - Hooks, J. J. PY - 2012 DA - 2012// TI - Regulation of VEGF expression in human retinal cells by cytokines: implications for the role of inflammation in age-related macular degeneration JO - J Cell Physiol VL - 227 UR - https://doi.org/10.1002/jcp.22708 DO - 10.1002/jcp.22708 ID - Nagineni2012 ER - TY - JOUR AU - Joussen, A. M. AU - Doehmen, S. AU - Le, M. L. AU - Koizumi, K. AU - Radetzky, S. AU - Krohne, T. U. PY - 2009 DA - 2009// TI - TNF-alpha mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations JO - Mol Vis VL - 15 ID - Joussen2009 ER - TY - JOUR AU - Huang, H. AU - Gandhi, J. K. AU - Zhong, X. AU - Wei, Y. AU - Gong, J. AU - Duh, E. J. PY - 2011 DA - 2011// TI - TNFalpha is required for late BRB breakdown in diabetic retinopathy, and its inhibition prevents leukostasis and protects vessels and neurons from apoptosis JO - Invest Ophthalmol Vis Sci VL - 52 UR - https://doi.org/10.1167/iovs.10-5768 DO - 10.1167/iovs.10-5768 ID - Huang2011 ER - TY - JOUR AU - Tracey, D. AU - Klareskog, L. AU - Sasso, E. H. AU - Salfeld, J. G. AU - Tak, P. P. PY - 2008 DA - 2008// TI - Tumor necrosis factor antagonist mechanisms of action: a comprehensive review JO - Pharmacol Ther VL - 117 UR - https://doi.org/10.1016/j.pharmthera.2007.10.001 DO - 10.1016/j.pharmthera.2007.10.001 ID - Tracey2008 ER - TY - JOUR AU - He, M. M. AU - Smith, A. S. AU - Oslob, J. D. AU - Flanagan, W. M. AU - Braisted, A. C. AU - Whitty, A. PY - 2005 DA - 2005// TI - Small-molecule inhibition of TNF-alpha JO - Science VL - 310 UR - https://doi.org/10.1126/science.1116304 DO - 10.1126/science.1116304 ID - He2005 ER - TY - JOUR AU - Kaistha, S. D. AU - Sinha, R. PY - 2009 DA - 2009// TI - Homology modeling of phosphoryl thymidine kinase of enterohemorrhagic Escherichia coli OH: 157 JO - Bioinformation. VL - 3 UR - https://doi.org/10.6026/97320630003240 DO - 10.6026/97320630003240 ID - Kaistha2009 ER - TY - JOUR AU - Koes, D. R. AU - Camacho, C. J. PY - 2012 DA - 2012// TI - ZINCPharmer: pharmacophore search of the ZINC database JO - Nucleic Acids Res VL - 40 UR - https://doi.org/10.1093/nar/gks378 DO - 10.1093/nar/gks378 ID - Koes2012 ER - TY - JOUR AU - Lipinski, C. A. AU - Lombardo, F. AU - Dominy, B. W. AU - Feeney, P. J. PY - 2001 DA - 2001// TI - Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings JO - Adv Drug Deliv Rev VL - 46 UR - https://doi.org/10.1016/S0169-409X(00)00129-0 DO - 10.1016/S0169-409X(00)00129-0 ID - Lipinski2001 ER - TY - JOUR AU - Teague, S. J. AU - Davis, A. M. AU - Leeson, P. D. AU - Oprea, T. PY - 1999 DA - 1999// TI - The design of leadlike combinatorial libraries JO - Angew Chem VL - 38 UR - https://doi.org/3.0.CO;2-U DO - 3.0.CO;2-U ID - Teague1999 ER - TY - JOUR AU - Waring, M. J. AU - Arrowsmith, J. AU - Leach, A. R. AU - Leeson, P. D. AU - Mandrell, S. AU - Owen, R. M. PY - 2015 DA - 2015// TI - An analysis of the attrition of drug candidates from four major pharmaceutical companies JO - Nat Rev Drug Discov VL - 14 UR - https://doi.org/10.1038/nrd4609 DO - 10.1038/nrd4609 ID - Waring2015 ER - TY - JOUR AU - Daina, A. AU - Michielin, O. AU - Zoete, V. PY - 2017 DA - 2017// TI - SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules JO - Sci Rep VL - 7 UR - https://doi.org/10.1038/srep42717 DO - 10.1038/srep42717 ID - Daina2017 ER - TY - JOUR AU - Daina, A. AU - Zoete, V. PY - 2016 DA - 2016// TI - A BOILED-egg to predict gastrointestinal absorption and brain penetration of small molecules JO - Chem Med Chem VL - 11 UR - https://doi.org/10.1002/cmdc.201600182 DO - 10.1002/cmdc.201600182 ID - Daina2016 ER - TY - JOUR AU - Apostolaki, M. AU - Armaka, M. AU - Victoratos, P. AU - Kollias, G. PY - 2010 DA - 2010// TI - Cellular mechanisms of TNF function in models of inflammation and autoimmunity JO - Curr Dir Autoimmun VL - 11 UR - https://doi.org/10.1159/000289195 DO - 10.1159/000289195 ID - Apostolaki2010 ER - TY - JOUR AU - Naismith, J. H. AU - Devine, T. Q. AU - Kohno, T. AU - Sprang, S. R. PY - 1996 DA - 1996// TI - Structures of the extracellular domain of the type I tumor necrosis factor receptor JO - Structure. VL - 4 UR - https://doi.org/10.1016/S0969-2126(96)00134-7 DO - 10.1016/S0969-2126(96)00134-7 ID - Naismith1996 ER - TY - JOUR AU - Chen, S. AU - Feng, Z. AU - Wang, Y. AU - Ma, S. AU - Hu, Z. AU - Yang, P. PY - 2017 DA - 2017// TI - Discovery of novel ligands for TNF-alpha and TNF receptor-1 through structure-based virtual screening and biological assay JO - J Chem Inf Model VL - 57 UR - https://doi.org/10.1021/acs.jcim.6b00672 DO - 10.1021/acs.jcim.6b00672 ID - Chen2017 ER - TY - JOUR AU - Saddala, M. S. AU - Kandimalla, R. AU - Adi, P. J. AU - Bhashyam, S. S. AU - Asupatri, U. R. PY - 2017 DA - 2017// TI - Novel 1,4-dihydropyridines for L-type calcium channel as antagonists for cadmium toxicity JO - Sci Rep VL - 7 UR - https://doi.org/10.1038/srep45211 DO - 10.1038/srep45211 ID - Saddala2017 ER - TY - JOUR AU - Guido, R. V. AU - Oliva, G. AU - Andricopulo, A. D. PY - 2008 DA - 2008// TI - Virtual screening and its integration with modern drug design technologies JO - Curr Med Chem VL - 15 UR - https://doi.org/10.2174/092986708783330683 DO - 10.2174/092986708783330683 ID - Guido2008 ER - TY - JOUR AU - Wolber, G. AU - Seidel, T. AU - Bendix, F. AU - Langer, T. PY - 2008 DA - 2008// TI - Molecule-pharmacophore superpositioning and pattern matching in computational drug design JO - Drug Discov Today VL - 13 UR - https://doi.org/10.1016/j.drudis.2007.09.007 DO - 10.1016/j.drudis.2007.09.007 ID - Wolber2008 ER - TY - JOUR AU - Smith, R. D. AU - Engdahl, A. L. AU - Dunbar, J. B. AU - Carlson, H. A. PY - 2012 DA - 2012// TI - Biophysical limits of protein-ligand binding JO - J Chem Inf Model VL - 52 UR - https://doi.org/10.1021/ci200612f DO - 10.1021/ci200612f ID - Smith2012 ER - TY - JOUR AU - Schwarm, A. AU - Ortmann, S. AU - Wolf, C. AU - Streich, W. J. AU - Clauss, M. PY - 2009 DA - 2009// TI - More efficient mastication allows increasing intake without compromising digestibility or necessitating a larger gut: comparative feeding trials in banteng (Bos javanicus) and pygmy hippopotamus (Hexaprotodon liberiensis) JO - Comp Biochem Physiol A VL - 152 UR - https://doi.org/10.1016/j.cbpa.2008.12.006 DO - 10.1016/j.cbpa.2008.12.006 ID - Schwarm2009 ER - TY - JOUR AU - Trott, O. AU - Olson, A. J. PY - 2010 DA - 2010// TI - AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading JO - J Comput Chem VL - 31 ID - Trott2010 ER - TY - JOUR AU - Yang, S. Y. PY - 2010 DA - 2010// TI - Pharmacophore modeling and applications in drug discovery: challenges and recent advances JO - Drug Discov Today VL - 15 UR - https://doi.org/10.1016/j.drudis.2010.03.013 DO - 10.1016/j.drudis.2010.03.013 ID - Yang2010 ER - TY - JOUR AU - Falvo, J. V. AU - Tsytsykova, A. V. AU - Goldfeld, A. E. PY - 2010 DA - 2010// TI - Transcriptional control of the TNF gene JO - Curr Dir Autoimmun VL - 11 UR - https://doi.org/10.1159/000289196 DO - 10.1159/000289196 ID - Falvo2010 ER - TY - JOUR AU - Zelova, H. AU - Hosek, J. PY - 2013 DA - 2013// TI - TNF-alpha signalling and inflammation: interactions between old acquaintances JO - Inflam Res VL - 62 UR - https://doi.org/10.1007/s00011-013-0633-0 DO - 10.1007/s00011-013-0633-0 ID - Zelova2013 ER - TY - JOUR AU - Eissner, G. AU - Kolch, W. AU - Scheurich, P. PY - 2004 DA - 2004// TI - Ligands working as receptors: reverse signaling by members of the TNF superfamily enhance the plasticity of the immune system JO - Cytokine Growth Factor Rev VL - 15 UR - https://doi.org/10.1016/j.cytogfr.2004.03.011 DO - 10.1016/j.cytogfr.2004.03.011 ID - Eissner2004 ER - TY - JOUR AU - Kim, O. T. AU - Le, M. D. AU - Trinh, H. X. AU - Nong, H. V. PY - 2016 DA - 2016// TI - In silico studies for the interaction of tumor necrosis factor-alpha (TNF-alpha) with different saponins from Vietnamese ginseng (Panax vietnamesis) JO - Biophys Physicobiol VL - 13 UR - https://doi.org/10.2142/biophysico.13.0_173 DO - 10.2142/biophysico.13.0_173 ID - Kim2016 ER - TY - JOUR AU - Zaka, M. AU - Abbasi, B. H. AU - Durdagi, S. PY - 2018 DA - 2018// TI - Proposing novel TNFalpha direct inhibitor Scaffolds using fragment-docking based e-pharmacophore modeling and binary QSAR-based virtual screening protocols pipeline JO - J Mol Graph Model VL - 85 UR - https://doi.org/10.1016/j.jmgm.2018.07.007 DO - 10.1016/j.jmgm.2018.07.007 ID - Zaka2018 ER - TY - JOUR AU - Geng, L. AU - Li, X. AU - Feng, X. AU - Zhang, J. AU - Wang, D. AU - Chen, J. PY - 2014 DA - 2014// TI - Association of TNF-alpha with impaired migration capacity of mesenchymal stem cells in patients with systemic lupus erythematosus JO - J Immunol Res VL - 2014 UR - https://doi.org/10.1155/2014/169082 DO - 10.1155/2014/169082 ID - Geng2014 ER - TY - JOUR AU - Prodeus, A. AU - Abdul-Wahid, A. AU - Fischer, N. W. AU - Huang, E. H. AU - Cydzik, M. AU - Gariepy, J. PY - 2015 DA - 2015// TI - Targeting the PD-1/PD-L1 immune evasion axis with DNA aptamers as a novel therapeutic strategy for the treatment of disseminated cancers JO - Mol Ther Nucleic Acids VL - 4 UR - https://doi.org/10.1038/mtna.2015.11 DO - 10.1038/mtna.2015.11 ID - Prodeus2015 ER - TY - JOUR AU - Cao, Y. AU - Li, Y. H. AU - Lv, D. Y. AU - Chen, X. F. AU - Chen, L. D. AU - Zhu, Z. Y. PY - 2016 DA - 2016// TI - Identification of a ligand for tumor necrosis factor receptor from Chinese herbs by combination of surface plasmon resonance biosensor and UPLC-MS JO - Anal Bioanal Chem VL - 408 UR - https://doi.org/10.1007/s00216-016-9633-6 DO - 10.1007/s00216-016-9633-6 ID - Cao2016 ER - TY - JOUR AU - Hu, Z. AU - Qin, J. AU - Zhang, H. AU - Wang, D. AU - Hua, Y. AU - Ding, J. PY - 2012 DA - 2012// TI - Japonicone A antagonizes the activity of TNF-alpha by directly targeting this cytokine and selectively disrupting its interaction with TNF receptor-1 JO - Biochem Pharmacol VL - 84 UR - https://doi.org/10.1016/j.bcp.2012.08.025 DO - 10.1016/j.bcp.2012.08.025 ID - Hu2012 ER - TY - JOUR AU - Choi, H. AU - Lee, Y. AU - Park, H. AU - Oh, D. S. PY - 2010 DA - 2010// TI - Discovery of the inhibitors of tumor necrosis factor alpha with structure-based virtual screening JO - Bioorg Med Chem Lett VL - 20 UR - https://doi.org/10.1016/j.bmcl.2010.08.116 DO - 10.1016/j.bmcl.2010.08.116 ID - Choi2010 ER -