Proteomic profiling of plasma biomarkers in acute ischemic stroke due to large vessel occlusion

Table 3 Correlation analysis of each biomarker with diagnosis

Proteins	OR^a (95% CI^a)	P^a value	OR^b (95% CI^b)	P^b value	AUC (95% CI)	P^c value
IGF2	17.365 (2.862–105.358)	0.002	47.564 (5.133–440.757)	0.001	0.731 (0.609–0.853)	0.001
LYVE1	10.320 (2.986–35.669)	< 0.001	7.707 (2.215–26.813)	0.001	0.813 (0.707–0.919)	< 0.001
PPBP	7.682 (2.201–26.813)	0.001	8.163 (1.903–35.014)	0.005	0.754 (0.638–0.870)	< 0.001
THBS1	13.282 (2.630–67.079)	0.002	14.132 (2.401–83.185)	0.003	0.769 (0.652–0.885)	< 0.001

AUC area under the receiver operating characteristic curve, OR odds ratio, CI confidence interval, IGF2 insulin like growth factor 2, LYVE1 lymphatic vessel endothelial hyaluronan receptor 1, PPBP pro-platelet basic protein, THBS1 thrombospondin 1
^aLogistic regression analysis, OR and 95% CI without adjusting
^bLogistic regression analysis, OR and 95% CI with adjusting for age, gender, blood pressure, medical history and blood test
^cReceiver operating characteristic curve analysis

ISSN: 1479-5876