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Table 3 Correlation analysis of each biomarker with diagnosis

From: Proteomic profiling of plasma biomarkers in acute ischemic stroke due to large vessel occlusion

Proteins ORa (95% CIa) Pa value ORb (95% CIb) Pb value AUC (95% CI) Pc value
IGF2 17.365 (2.862–105.358) 0.002 47.564 (5.133–440.757) 0.001 0.731 (0.609–0.853) 0.001
LYVE1 10.320 (2.986–35.669) < 0.001 7.707 (2.215–26.813) 0.001 0.813 (0.707–0.919) < 0.001
PPBP 7.682 (2.201–26.813) 0.001 8.163 (1.903–35.014) 0.005 0.754 (0.638–0.870) < 0.001
THBS1 13.282 (2.630–67.079) 0.002 14.132 (2.401–83.185) 0.003 0.769 (0.652–0.885) < 0.001
  1. AUC area under the receiver operating characteristic curve, OR odds ratio, CI confidence interval, IGF2 insulin like growth factor 2, LYVE1 lymphatic vessel endothelial hyaluronan receptor 1, PPBP pro-platelet basic protein, THBS1 thrombospondin 1
  2. aLogistic regression analysis, OR and 95% CI without adjusting
  3. bLogistic regression analysis, OR and 95% CI with adjusting for age, gender, blood pressure, medical history and blood test
  4. cReceiver operating characteristic curve analysis