Table 2 Comparison of CR rates between DNMT3A R882 mutation and wild type patients after one or two courses of induction therapy
Chemotherapy cycles | Total CR/n (%) | R882 wild-type CR/n (%) | R882 mutation CR/n (%) | OR (95% CI) | P value |
|---|---|---|---|---|---|
One cycle | 357/864 (41.32) | 336/791 (42.48) | 21/73 (28.77) | 1.829 (1.081–3.094) | 0.023 |
Two cycles | 601/864 (69.56) | 556/791 (70.29) | 45/73 (61.64) | 1.472 (0.897–2.417) | 0.124 |