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Table 2 Crude and adjusted hazard ratios for association between SUA categorized by quartiles and new-onset hypertension

From: Mediation of the effect of serum uric acid on the risk of developing hypertension: a population-based cohort study

SUA

Q1

Q2

Q3

Q4

P for trende

Range (mg/dL)

< 3.5

3.5–4.2

4.3–5.0

> 5.0

–

Events

487

567

569

725

–

Person-years

6965.6

7511.0

7177.7

7781.9

–

Crudea

Ref (1)

1.08 (0.96–1.22)

1.16 (1.02–1.31)

1.39 (1.23–1.56)

< 0.001

Model 1b

Ref (1)

1.03 (0.91–1.17)

1.12 (0.99–1.27)

1.25 (1.10–1.42)

< 0.001

Model 2c

Ref (1)

1.02 (0.90–1.16)

1.10 (0.96–1.25)

1.20 (1.06–1.37)

< 0.001

Model 3d

Ref (1)

1.01 (0.89–1.15)

1.07 (0.94–1.22)

1.16 (1.02–1.33)

0.003

  1. aCrude: stratified by age
  2. bModel 1: stratified by age and simultaneously adjusted for gender, educational level, marital status, cigarette smoking, alcohol intaking, sleep duration, disability, depressive symptoms, grip, SBP, DBP
  3. cModel 2: as for model 1 and further adjusted for FPG, TG, TC, HDL, HbA1c, BMI, WC
  4. dModel 3: as for model 2 and simultaneously adjusted for BUN, LDL, CRP, PR, CRE
  5. eP value was calculated by the Mantel extension test for linear trends, and the median values of each category of SUA were included in the model as a continuous variable