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Table 2 Crude and adjusted hazard ratios for association between SUA categorized by quartiles and new-onset hypertension

From: Mediation of the effect of serum uric acid on the risk of developing hypertension: a population-based cohort study

SUA Q1 Q2 Q3 Q4 P for trende
Range (mg/dL) < 3.5 3.5–4.2 4.3–5.0 > 5.0
Events 487 567 569 725
Person-years 6965.6 7511.0 7177.7 7781.9
Crudea Ref (1) 1.08 (0.96–1.22) 1.16 (1.02–1.31) 1.39 (1.23–1.56) < 0.001
Model 1b Ref (1) 1.03 (0.91–1.17) 1.12 (0.99–1.27) 1.25 (1.10–1.42) < 0.001
Model 2c Ref (1) 1.02 (0.90–1.16) 1.10 (0.96–1.25) 1.20 (1.06–1.37) < 0.001
Model 3d Ref (1) 1.01 (0.89–1.15) 1.07 (0.94–1.22) 1.16 (1.02–1.33) 0.003
  1. aCrude: stratified by age
  2. bModel 1: stratified by age and simultaneously adjusted for gender, educational level, marital status, cigarette smoking, alcohol intaking, sleep duration, disability, depressive symptoms, grip, SBP, DBP
  3. cModel 2: as for model 1 and further adjusted for FPG, TG, TC, HDL, HbA1c, BMI, WC
  4. dModel 3: as for model 2 and simultaneously adjusted for BUN, LDL, CRP, PR, CRE
  5. eP value was calculated by the Mantel extension test for linear trends, and the median values of each category of SUA were included in the model as a continuous variable