Unilateral L4-dorsal root ganglion stimulation evokes pain relief in chronic neuropathic postsurgical knee pain and changes of inflammatory markers: part II whole transcriptome profiling

Table 2 Baseline and follow-up values of peripheral concentrations (given in pg/ml, exceptional for HMGB-1 ng/ml) of pro- and anti-inflammatory mediators

Pat. no.	HMGB1_bs	HMGB1_as	IL-1β_bs	IL-1β_as	TNFα_bs	TNFα_as	IL-6_bs	IL-6_as	IL-10_bs	IL-10_as
1	1.956	2.368	0.136	0.065	2.414	2.318	2.759	2.083	22.667	0.000
2	5.897	5.574	0.140	0.070	2.136	2.291	3.524	6.800	32.000	0.000
3	1.838	4.309	0.117	0.201	1.886	1.886	2.566	4.455	25.333	0.000
4	4.397	2.691	0.229	0.089	1.259	1.350	3.862	0.897	40.000	16.667
5	38.691	5.338	0.369	0.201	1.914	1.986	12.041	2.855	0.667	14.667
6	4.515	2.897	0.014	0.056	0.986	1.059	2.490	1.793	0.667	0.000
7	6.868	4.338	0.336	0.350	1.877	1.918	15.462	17.614	7.333	24.000
8	9.132	1.544	0.140	0.103	1.545	1.500	4.462	3.359	76.000	10.667
9	2.485	1.662	0.121	0.093	1.605	1.818	2.090	1.352	94.000	1.333
10	9.868	11.838	0.103	0.131	1.936	1.236	12.903	16.193	59.333	4.667
11	3.603	4.544	0.131	0.173	1.423	1.477	2.566	5.690	60.667	6.000
12	2.544	4.397	0.065	0.150	1.691	1.709	2.538	3.407	38.000	13.333

Pat. no.	Ghrelin_bs	Ghrelin_as	Adiponectin_bs	Adiponectin_as	Leptin_bs	Leptin_as	BDNF_bs	BDNF_as	Oxytocin_bs	Oxytocin_as
1	3895.376	5059.584	10,670	11,340	258,300	219,500	45,790.48	53,552.38	39.7	59.9
2	2622.864	2387.712	8610	8200	11,100	17,000	44,266.67	44,933.33	33.7	42.5
3	4873.856	3762.032	4440	4190	70,600	75,200	34,838.10	23,266.67	22.5	49.5
4	4134.976	13045.936	8730	19,330	49,800	28,200	29,457.14	41,409.52	31.3	15
5	4203.376	3793.04	2110	4300	5600	7400	54,838.10	47,361.90	15	111.2
6	6972.928	8809.568	8760	12,500	23,800	7700	23,076.19	33,980.95	23.9	87.6
7	2374.272	2223.344	6860	3460	40,500	85,000	34,266.67	36,504.76	20.7	15
8	2858.688	2493.792	1650	1300	63,000	56,100	27,742.86	29,933.33	23.1	116.1
9	14,335.92	12126.912	10,620	7230	54,300	45,800	41,171.43	39,266.67	28.7	15
10	10885.504	5767.136	7800	6270	45,300	47,900	35,314.29	42,076.19	15	17.5
11	4144.784	4280.784	28,850	22,450	31,800	36,000	49,742.86	34,647.62	61.4	24.6
12	2387.712	1824.88	4250	3610	135,000	105,900	52,600.00	37,457.14	39.5	119.1

ISSN: 1479-5876