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Table 3 Correlations between blood platelet count and the densities of tumor infiltrating immune cells

From: Platelet count, aspirin use, and characteristics of host inflammatory responses in colorectal cancer

Variable

N (unadjusted, adjusted)

Unadjusted

Adjusted

Pearson r

p value

Beta

p value

CD3 IM

354, 352

0.035

0.511

0.033

0.503

CD3 CT

355, 353

− 0.021

0.694

0.015

0.761

CD3 IEL

352, 350

0.058

0.280

0.029

0.565

CD8 IM

355, 353

0.097

0.068

0.057

0.272

CD8 CT

355, 353

− 0.017

0.752

− 0.032

0.513

CD8 IEL

345, 344

0.062

0.247

0.033

0.519

FoxP3 IM

354, 352

− 0.055

0.301

− 0.007

0.899

FoxP3 CT

354, 352

− 0.108

0.043

− 0.054

0.281

Mast cell tryptase IM

354, 352

− 0.119

0.025

− 0.054

0.255

Mast cell tryptase CT

354, 352

− 0.078

0.143

0.008

0.867

Neutrophil elastase IM

347, 345

0.015

0.776

0.035

0.470

Neutrophil elastase CT

347, 345

0.042

0.435

0.000

1.000

  1. Blood platelet count and immune cell densities were logarithmically transformed because of positive skewness. The correlations were adjusted for tumor location (colon vs. rectum), preoperative radiotherapy or chemoradiotherapy, tumor stage variables (T1–2 vs. T3–4; N0 vs. N1–2; M0 vs. M1), patient age, patient gender, and blood hemoglobin levels with multiple linear regression
  2. IM: invasive margin; CT: center of tumor; IEL: intraepithelial