From: Platelet count, aspirin use, and characteristics of host inflammatory responses in colorectal cancer
Variable | Blood platelet count (109/L), mean (sd) | p value |
---|---|---|
All patients, n = 356 | 294.9 (93.4) | |
Age | ||
< 65, n = 130 | 308.0 (94.0) | 0.044 |
= 65, n = 226 | 287.4 (92.4) | |
Gender | ||
Male, n = 190 | 280.9 (97.3) | 0.002 |
Female, n = 166 | 310.9 (86.3) | |
Body mass index | ||
< 25, n = 123 | 298.7 (102.2) | 0.688 |
25–30, n = 146 | 288.8 (81.5) | |
> 30, n = 78 | 293.5 (100.5) | |
Tumor location | ||
Proximal colon, n = 123 | 319.4 (90.6) | < 0.001 |
Distal colon, n = 73 | 301.7 (102.2) | |
Rectum, n = 160 | 273.0 (86.4) | |
Neoadjuvant therapy in rectal cancer patients | ||
No, n = 91 | 279.0 (95.7) | 0.295 |
Yes, n = 69 | 265.0 (72.4) | |
WHO grade | ||
Low-grade (1–2), n = 308 | 293.1 (93.2) | 0.406 |
High-grade (3), n = 46 | 305.4 (96.3) | |
Stage | ||
Stage I, n = 81 | 275.0 (69.6) | < 0.001 |
Stage II, n = 113 | 296.8 (91.8) | |
Stage III, n = 116 | 283.5 (87.6) | |
Stage IV, n = 45 | 351.2 (122.0) | |
T class | ||
T1, n = 15 | 271.4 (81.7) | 0.003 |
T2, n = 89 | 270.6 (64.5) | |
T3, n = 225 | 299.1 (95.0) | |
T4, n = 26 | 355.8 (134.4) | |
N class | ||
N0, n = 201 | 289.2 (84.8) | 0.124 |
N1, n = 96 | 291.5 (98.0) | |
N2, n = 57 | 317.4 (109.5) | |
M class | ||
M0, n = 311 | 286.8 (85.7) | 0.001 |
M1, n = 45 | 351.2 (122.0) | |
Lymphatic invasion | ||
No, n = 192 | 287.9 (85.7) | 0.162 |
Yes, n = 160 | 302.1 (101.4) | |
Blood vessel invasion | ||
No, n = 293 | 291.4 (89.3) | 0.263 |
Yes, n = 59 | 308.7 (110.8) | |
Mismatch repair enzyme status | ||
Proficient, n = 315 | 290.1 (92.4) | 0.006 |
Deficient, n = 40 | 332.9 (94.9) | |
BRAF VE1 immunohistochemistry | ||
Negative, n = 322 | 292.7 (93.8) | 0.126 |
Positive, n = 33 | 318.8 (87.3) | |
Modified Glasgow Prognostic Score | ||
mGPS0, n = 269 | 283.1 (86.3) | < 0.001 |
mGPS1, n = 63 | 335.7 (101.5) | |
mGPS2, n = 8 | 413.2 (148.2) | |
Anemia | ||
No, n = 202 | 264.5 (73.7) | < 0.001 |
Yes, n = 154 | 334.8 (101.4) | |
Anemia category | ||
No anemia, n = 202 | 264.5 (73.7) | 0.005 |
Microcytic anemia, n = 43 | 372.8 (113.4) | |
Normocytic anemia, n = 109 | 322.6 (91.5) | |
Macrocytic anemia, n = 2 | 181.0 (58.0) | |
Aspirin use | ||
No, n = 271 | 297.3 (90.5) | 0.396 |
Yes, n = 85 | 287.4 (102.3) |