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Table 1 General data of the AAV patients

From: The expression of NOD2, NLRP3 and NLRC5 and renal injury in anti-neutrophil cytoplasmic antibody-associated vasculitis

Parameters

Value

Number

34

Gender (male/female)

12/22

Age at diagnosis

61.7 ± 11.9

MPO-ANCA/PR3-ANCA

30/4

ESR (mm/1 h)

65.8 ± 39.2

Scr (μmol/L)

266.9 (196.3–410.0)

Proteinuria (g/24 h)

1.42 ± 1.25

Clinical manifestation

 Skin rash

5 (14.7%)

 Arthralgia

3 (8.8%)

 Muscle pain

5 (14.7%)

 Pulmonary

18 (52.9%)

 ENT

10 (29.4%)

 Ophthalmic

10 (29.4%)

 Gastrointestinal

3 (8.8%)

 Nervous

5 (14.7%)

BVAS

18.6 ± 5.2

Glomeruli per biopsy

30.0 ± 13.8

Glomerular lesions (%)

 Total crescents

62.2 ± 21.0

 Fibrinoid necrosis

1.3 (0–6.6)

 Glomerulosclerosis

2.7 (0–10.0)

Tubulointerstitial lesions

 Tubular atrophy (−/+/++)

5/25/4

 Interstitial infiltration (−/+/++/+++ )

0/8/21/5

 Interstitial fibrosis (−/+/++)

3/25/6

Berden classification n (%)

 Focal

5 (14.7)

 Crescentic

24 (70.6)

 Mixed

5 (14.7)

 Sclerotic

0 (0)

  1. Statistics are shown as mean ± standard deviation or median (IQR) for different distributions
  2. ESR erythrocyte sedimentation rate, Scr serum creatinine, ENT ear, nose and throat, BVAS Birmingham Vasculitis Activity Score