Table 1 Univariable analyses of overall survival (OS) of AML patients from TCGA database
From: CEBPE expression is an independent prognostic factor for acute myeloid leukemia
Variable | HR | 95% CI | P-value |
|---|---|---|---|
CEBPE, high vs. low | 0.5 | 0.3–0.7 | 0.00029 |
Age, ≥ 60 vs. < 60 | 3.2 | 2.2–4.6 | 9.40E−10 |
log2 (WBC), each 2-unit increase | 1.2 | 1.0–1.4 | 0.040 |
FLT3, FLT3-ITD vs. others | 1.4 | 0.9–2.1 | 0.094 |
NPM1, mutation vs. wild-type | 1.4 | 1.0–2.1 | 0.071 |
DNMT3A, mutation vs. wild-type | 1.8 | 1.2–2.6 | 0.0049 |
RUNX1, mutation vs. wild-type | 1.7 | 1.0–2.9 | 0.063 |
TP53, mutation vs. wild-type | 3.4 | 1.9–5.9 | 1.98E−05 |
inv(16) vs. others | 0.3 | 0.1–0.9 | 0.032 |
t(15;17) vs. others | 0.3 | 0.1–0.7 | 0.0075 |
t(9;11) vs. others | 4.1 | 1.0–16.9 | 0.052 |
t(9;22) vs. others | 3.4 | 0.8–14.1 | 0.086 |
del (3) vs. others | 2.0 | 0.8–4.1 | 0.097 |