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Table 1 Univariable analyses of overall survival (OS) of AML patients from TCGA database

From: CEBPE expression is an independent prognostic factor for acute myeloid leukemia

Variable HR 95% CI P-value
CEBPE, high vs. low 0.5 0.3–0.7 0.00029
Age, ≥ 60 vs. < 60 3.2 2.2–4.6 9.40E−10
log2 (WBC), each 2-unit increase 1.2 1.0–1.4 0.040
FLT3, FLT3-ITD vs. others 1.4 0.9–2.1 0.094
NPM1, mutation vs. wild-type 1.4 1.0–2.1 0.071
DNMT3A, mutation vs. wild-type 1.8 1.2–2.6 0.0049
RUNX1, mutation vs. wild-type 1.7 1.0–2.9 0.063
TP53, mutation vs. wild-type 3.4 1.9–5.9 1.98E−05
inv(16) vs. others 0.3 0.1–0.9 0.032
t(15;17) vs. others 0.3 0.1–0.7 0.0075
t(9;11) vs. others 4.1 1.0–16.9 0.052
t(9;22) vs. others 3.4 0.8–14.1 0.086
del (3) vs. others 2.0 0.8–4.1 0.097
  1. HR hazard ratio, 95% CI 95% confidence interval, WBC white blood cell, ITD internal tandem duplication
  2. Variables for which P < 0.1 in univariable models were shown