Fig. 6

Tumor mutation burden of gastric cancer. a The distribution of TMB across all tumors, using a threshold of low (1–5 mutations/Mb), intermediate (6–19 mutations/Mb), and high (≥ 20 mutations/Mb). Non-parametric test of TMB according to DDR genes (b) and TP53 (c) genotype, Lauren classification (d), differentiation (e), and HER2 status (f)