| Male | Female | ||||||
---|---|---|---|---|---|---|---|---|
Control | 5Â mg/kg | 10Â mg/kg | 15Â mg/kg | Control | 5Â mg/kg | 10Â mg/kg | 15Â mg/kg | |
BUN (mg/dL) | 30 ± 9.7 | 26 ± 2.2 | 31 ± 7.3 | 23 ± 2.9 | 22 ± 5.2 | 19 ± 2.2 | 19 ± 3.0 | 22 ± 2.5 |
ALP (IU/L) | 54 ± 12.9 | 68 ± 13.8 | 73 ± 19.7 | 58 ± 10.5 | 95 ± 38.8 | 88 ± 33.2 | 70 ± 48.4 | 62 ± 18.4 |
ALT (IU/L) | 107 ± 29.7 | 124 ± 71.5 | 96 ± 28.3 | 67 ± 32.3 | 88 ± 22.8 | 79 ± 35.0 | 61 ± 18.5 | 90 ± 27.2 |
AST (IU/L) | 87 ± 28.5 | 92 ± 28.6 | 83 ± 23.6 | 63 ± 13.5 | 107 ± 16.2 | 80 ± 8.3a | 83 ± 19.0 | 93 ± 12.5 |
TBIL (mg/dL) | 0.1 ± 0.04 | 0.2 ± 0.05 | 0.2 ± 0.04 | 0.2 ± 0.05 | 0.2 ± 0 | 0.2 ± 0.05 | 0.1 ± 0.05 | 0.1 ± 0b |
N | 5 | 4 | 5 | 4 | 5 | 5 | 5 | 4 |