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Table 2 OI Group Demographic

From: Orthostatic intolerance in chronic fatigue syndrome

  No OI Controls
N = 21
Postural OI Controls
N = 4
No OI CFS
N = 11
Persistent OI CFS
N = 16
Postural OI CFS
N = 12
ANOVA
Age 44 ± 18 41 ± 25 44 ± 9 51 ± 15 46 ± 13 ns
Males 13 1 3 5 3 ns
Females 8 3 8 11 9 ns
BMI 28.74 ± 4.56 22.15 ± 1.71 25.8 ± 4.7 25.9 ± 4.6 27.6 ± 7.2 ns
COMPASS-31 [13]       
COMPASS-31 Sum 12.06 ± 8.60* 29.09 ± 7.96 22.40 ± 15.26 36.45 ± 9.10 27.25 ± 15.37 ns
OI 6.11 ± 7.10* 19.00 ± 11.49 12.40 ± 10.23 17.14 ± 8.22 13.45 ± 8.81 ns
Vasomotor 0* 0 0 0.65 ± 0.93 0.98 ± 0.97 p < 0.001
Secretomotor 1.47 ± 2.03* 2.68 ± 3.21 1.50 ± 2.68 5.66 ± 3.72 2.73 ± 3.72 p < 0.001
GI 3.01 ± 3.52* 5.80 ± 3.30 5.09 ± 3.62 9.37 ± 3.48 6.90 ± 4.89 p < 0.001
Bladder 0.58 ± 1.19 0.28 ± 0.56 0.78 ± 1.18 1.11 ± 1.63 1.21 ± 1.44 ns
Pupillomotor 0.89 ± 0.57* 1.33 ± 0.90 2.63 ± 1.17 2.50 ± 0.61 1.97 ± 0.71 p < 0.001
CFS_Q_Fatigue [20] 0.94 ± 1.11* 2.50 ± 1.29* 3.27 ± 1.19 3.53 ± 0.64 3.42 ± 0.67 p < 0.001
CFS_Q_Sum8 [20] 4.72 ± 5.17* 11.25 ± 2.75* 16.64 ± 6.30 19.60 ± 5.05 17.17 ± 4.45 p < 0.001
Chalder_11 [27] 11.63 ± 4.13* 18.00 ± 7.66* 20.36 ± 7.10 23.73 ± 5.79 24.00 ± 6.34 p < 0.001
SF-36 [28]       
Physical functioning 88.68 ± 21.72* 87.50 ± 10.41* 52.73 ± 33.57 44.33 ± 24.12 42.50 ± 22.21 p < 0.001
Role—physical 90.79 ± 12.54* 25.00 ± 48.99* 20.45 ± 40.03 6.67 ± 17.59 2.08 ± 7.22 p < 0.001
Role—emotional 92.28 ± 21.02 50.00 ± 57.54 57.58 ± 47.35 68.89 ± 46.23 83.33 ± 38.92 ns
Vitality 75.79 ± 19.51* 36.75 ± 20.55* 40.73 ± 27.46 28.07 ± 23.85 37.00 ± 18.12 p < 0.001
Mental Health 77.26 ± 13.54 57.00 ± 27.59 63.64 ± 10.95 66.93 ± 20.03 72.00 ± 17.14 ns
Social function 88.16 ± 17.42* 46.88 ± 27.72* 43.18 ± 33.24 27.50 ± 21.75 29.17 ± 26.29 p < 0.001
Bodily pain 87.63 ± 15.79* 76.50 ± 37.11* 48.82 ± 30.35 42.40 ± 22.70 50.17 ± 29.29 p < 0.001
General Health 75.79 ± 19.51* 36.75 ± 20.55* 40.73 ± 27.46 28.07 ± 23.85 37.00 ± 18.12 p < 0.001
  1. There were no significant differences in demographics between groups. The 3 CFS groups were significantly different from both SC groups for measures of autonomic dysfunction, cognitive dysfunction, fatigue, pain, and quality of life (p < 0.05, Tukey’s HSD). The CFS Persistent OI group had significantly higher scores on the COMPASS-31 than the CFS No OI group and scored significantly higher on headache, neurological, and ear/sinus-related questions on a systemic complaints questionnaire (p < 0.05, Tukey’s HSD)