Skip to main content

Table 1 Baseline and procedural characteristics according to time-of-day at symptom onset

From: Time-of-day at symptom onset was not associated with infarct size and long-term prognosis in patients with ST-segment elevation myocardial infarction

Characteristic Time of symptom onset (hours) p-value
0–6
n = 273 (22.6%)
6–12
n = 355 (29.4%)
12–18
n = 309 (25.6%)
18–24
n = 269 (22.3%)
Age, years 61.4 ± 13 62.0 ± 12.8 62.8 ± 13.6 62.9 ± 12.5 0.45
Women, n (%) 64 (23.4) 100 (28.2) 65 (21.0) 57 (21.2) 0.11
Diabetes mellitus, n (%) 60 (22.0) 62 (17.5) 55 (17.8) 52 (19.3) 0.49
BMI, kg/m2 26.2 (24.2;28.9) 26.3 (24.2;29) 26.2 (24.1;28.6) 26.1 (24.2;28.6) 0.85
Hypertension, n (%) 202 (74) 244 (68.7) 220 (71.2) 180 (66.9) 0.29
Hypercholesterolemia, n (%) 163 (59.7) 199 (56.1) 148 (47.9) 140 (52.0) 0.03
Current smoker, n (%) 122 (44.7) 143 (40.3) 127 (41.1) 125 (46.5) 0.37
Prior MI, n (%) 36 (13.2) 38 (10.7) 42 (13.6) 35 (13.0) 0.67
Prior CABG, n (%) 10 (3.7) 14 (3.9) 6 (1.9) 9 (3.3) 0.50
Anterolateral location of MI, n (%) 169 (61.9) 195 (54.9) 199 (64.4) 152 (56.5) 0.05
Killip class ≥ 2, n (%) 76 (27.8) 98 (27.6) 72 (23.3) 65 (24.2) 0.46
ST-segment resolution,  % 50.1 (20.4;76) 55.5 (28.5;77.3) 48.1 (22.3;74.3) 56.4 (29.4;76.7) 0.36
GFR, mL/min 86.3 (64.2;108.9) 84.5 (64.4;109.2) 83.3 (63.7;105.9) 82.9 (61.5;106.5) 0.57
Time to admission, hours 6.5 (3.3;11) 3.5 (1.8;6.2) 3.8 (1.8;8.9) 5.0 (2.2;14.3) < 0.0001
Door to balloon, hours 1.3 (0.9;1.8) 1.2 (0.8;1.6) 1.2 (0.8;1.7) 1.3 (1;1.8) 0.02
Multivessel disease, n (%) 175 (64.1) 218 (61.4) 203 (65.7) 182 (67.7) 0.41
Baseline TIMI flow grade 0.63
 0, n (%) 130 (47.6) 169 (47.6) 140 (45.3) 128 (47.6)  
 1, n (%) 41 (15.0) 37 (10.4) 35 (11.3) 24 (8.9)  
 2, n (%) 57 (20.9) 83 (23.4) 76 (24.6) 63 (23.4)  
 3, n (%) 45 (16.5) 66 (18.6) 58 (18.8) 54 (20.1)  
No reflow, n (%) 33 (12.1) 50 (14.1) 48 (15.5) 35 (13.0) 0.66
Type of intervention 0.50
 Stenting, n (%) 237 (86.8) 307 (86.5) 261 (84.5) 239 (88.8)  
 Balloon angioplasty, n (%) 36 (13.2) 48 (13.5) 48 (15.5) 30 (11.2)  
LV-EF, % 49 (41;57) 51 (44;59) 49 (41;55) 49 (43;56) 0.13
Infarct vessel 0.48
 LM, n (%) 1 (0.4) 2 (0.6) 1 (0.3) 0 (0)  
 LAD, n (%) 117 (42.9) 153 (43.1) 154 (49.8) 115 (42.8)  
 LCx, n (%) 55 (20.1) 50 (14.1) 47 (15.2) 50 (18.6)  
 RCA, n (%) 94 (34.4) 144 (40.6) 102 (33.0) 99 (36.8)  
 CABG, n (%) 6 (2.2) 6 (1.7) 5 (1.6) 5 (1.9)  
Presentation during office hours 143 (52.4) 275 (77.5) 169 (54.7) 79 (29.5) < 0.0001
  1. Data are presented as mean ± standard deviation or median (25th–75th percentiles) or counts (%)
  2. BMI body mass index, CABG coronary artery bypass graft, GFR glomerular filtration rate, LV-EF left ventricular ejection fraction, LAD left anterior descending artery, LCX left circumflex artery, LM left mainstem, MI myocardial infarction, RCA right coronary artery