Table 1 Baseline and procedural characteristics according to time-of-day at symptom onset
Characteristic | Time of symptom onset (hours) | p-value | |||
|---|---|---|---|---|---|
0–6 n = 273 (22.6%) | 6–12 n = 355 (29.4%) | 12–18 n = 309 (25.6%) | 18–24 n = 269 (22.3%) | ||
Age, years | 61.4 ± 13 | 62.0 ± 12.8 | 62.8 ± 13.6 | 62.9 ± 12.5 | 0.45 |
Women, n (%) | 64 (23.4) | 100 (28.2) | 65 (21.0) | 57 (21.2) | 0.11 |
Diabetes mellitus, n (%) | 60 (22.0) | 62 (17.5) | 55 (17.8) | 52 (19.3) | 0.49 |
BMI, kg/m2 | 26.2 (24.2;28.9) | 26.3 (24.2;29) | 26.2 (24.1;28.6) | 26.1 (24.2;28.6) | 0.85 |
Hypertension, n (%) | 202 (74) | 244 (68.7) | 220 (71.2) | 180 (66.9) | 0.29 |
Hypercholesterolemia, n (%) | 163 (59.7) | 199 (56.1) | 148 (47.9) | 140 (52.0) | 0.03 |
Current smoker, n (%) | 122 (44.7) | 143 (40.3) | 127 (41.1) | 125 (46.5) | 0.37 |
Prior MI, n (%) | 36 (13.2) | 38 (10.7) | 42 (13.6) | 35 (13.0) | 0.67 |
Prior CABG, n (%) | 10 (3.7) | 14 (3.9) | 6 (1.9) | 9 (3.3) | 0.50 |
Anterolateral location of MI, n (%) | 169 (61.9) | 195 (54.9) | 199 (64.4) | 152 (56.5) | 0.05 |
Killip class ≥ 2, n (%) | 76 (27.8) | 98 (27.6) | 72 (23.3) | 65 (24.2) | 0.46 |
ST-segment resolution, Â % | 50.1 (20.4;76) | 55.5 (28.5;77.3) | 48.1 (22.3;74.3) | 56.4 (29.4;76.7) | 0.36 |
GFR, mL/min | 86.3 (64.2;108.9) | 84.5 (64.4;109.2) | 83.3 (63.7;105.9) | 82.9 (61.5;106.5) | 0.57 |
Time to admission, hours | 6.5 (3.3;11) | 3.5 (1.8;6.2) | 3.8 (1.8;8.9) | 5.0 (2.2;14.3) | < 0.0001 |
Door to balloon, hours | 1.3 (0.9;1.8) | 1.2 (0.8;1.6) | 1.2 (0.8;1.7) | 1.3 (1;1.8) | 0.02 |
Multivessel disease, n (%) | 175 (64.1) | 218 (61.4) | 203 (65.7) | 182 (67.7) | 0.41 |
Baseline TIMI flow grade | 0.63 | ||||
 0, n (%) | 130 (47.6) | 169 (47.6) | 140 (45.3) | 128 (47.6) |  |
 1, n (%) | 41 (15.0) | 37 (10.4) | 35 (11.3) | 24 (8.9) |  |
 2, n (%) | 57 (20.9) | 83 (23.4) | 76 (24.6) | 63 (23.4) |  |
 3, n (%) | 45 (16.5) | 66 (18.6) | 58 (18.8) | 54 (20.1) |  |
No reflow, n (%) | 33 (12.1) | 50 (14.1) | 48 (15.5) | 35 (13.0) | 0.66 |
Type of intervention | 0.50 | ||||
 Stenting, n (%) | 237 (86.8) | 307 (86.5) | 261 (84.5) | 239 (88.8) |  |
 Balloon angioplasty, n (%) | 36 (13.2) | 48 (13.5) | 48 (15.5) | 30 (11.2) |  |
LV-EF, % | 49 (41;57) | 51 (44;59) | 49 (41;55) | 49 (43;56) | 0.13 |
Infarct vessel | 0.48 | ||||
 LM, n (%) | 1 (0.4) | 2 (0.6) | 1 (0.3) | 0 (0) |  |
 LAD, n (%) | 117 (42.9) | 153 (43.1) | 154 (49.8) | 115 (42.8) |  |
 LCx, n (%) | 55 (20.1) | 50 (14.1) | 47 (15.2) | 50 (18.6) |  |
 RCA, n (%) | 94 (34.4) | 144 (40.6) | 102 (33.0) | 99 (36.8) |  |
 CABG, n (%) | 6 (2.2) | 6 (1.7) | 5 (1.6) | 5 (1.9) |  |
Presentation during office hours | 143 (52.4) | 275 (77.5) | 169 (54.7) | 79 (29.5) | < 0.0001 |