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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Overexpression of microRNA-195-5p reduces cisplatin resistance and angiogenesis in ovarian cancer by inhibiting the PSAT1-dependent GSK3β/β-catenin signaling pathway

Fig. 1

miR-195-5p affects OC progression via PSAT1-mediated GSK3β/β-catenin signaling pathway. a Intersection of the top 100 DEGs from datasets GSE54388, GSE40595, GSE38666, GSE18520 and GSE14407; b the PPI network of OC-related DEGs and disease genes where the arrow means DEGs, and the circle represents disease genes; c, d heat map of the top 50 DEGs in GSE54388 and GSE40595, where the abscissa represents the sample number, and the ordinate represents the DEG; upper right histogram is the color gradation where each rectangle corresponds to a sample expression value; eg the expression of PSAT1 in datasets GSE38666, GSE18520 and GSE14407. h Intersection of predicted miRNAs that target PSAT1 in databases TargetScan, mirDIP, miRopath, microRNA, DIANA and miRSearch

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