Univariable | Multivaraible | |||||||
---|---|---|---|---|---|---|---|---|
p-value | HR | 95% CI | p-value | HR | 95% CI | |||
Total | ||||||||
CD163 High vs Low | 0.014 | 1.334 | 1.059 | 1.273 | 0.024* | 1.335 | 1.04 | 1.715 |
PD-L1 Pos vs Neg | < 0.001 | 0.521 | 0.396 | 0.687 | 0.087 | 0.775 | 0.579 | 1.038 |
CD3 High vs Low | 0.031 | 0.776 | 0.616 | 0.978 | 0.456 | 0.906 | 0.698 | 1.175 |
CD8 High vs Low | 0.008 | 0.731 | 0.58 | 0.921 | 0.037* | 0.75 | 0.573 | 0.982 |
FOXP3lowCD163low | 0.012 | 0.719 | 0.557 | 0.929 | ||||
Stage I–II | ||||||||
FOXP3 High vs Low | < 0.001 | 0.231 | 0.112 | 0.474 | < 0.001* | 0.207 | 0.100 | 0.426 |
Stage III–IV | ||||||||
CD8 High vs Low | 0.005 | 0.694 | 0.537 | 0.897 | 0.003* | 0.661 | 0.502 | 0.871 |
FOXP3lowCD163low | < 0.001 | 0.547 | 0.408 | 0.734 | < 0.001* | 0.561 | 0.407 | 0.774 |
N+ | ||||||||
PD-L1 Pos vs Neg | 0.001 | 0.535 | 0.373 | 0.768 | 0.011* | 0.621 | 0.431 | 0.895 |
CD3 High vs Low | 0.017 | 0.728 | 0.561 | 0.946 | 0.333 | 0.864 | 0.643 | 1.161 |
CD8 High vs Low | 0.004 | 0.679 | 0.523 | 0.883 | 0.035* | 0.719 | 0.53 | 0.977 |
FOXP3lowCD163low | 0.003 | 0.651 | 0.488 | 0.868 | 0.007* | 0.654 | 0.479 | 0.892 |
Upper | ||||||||
FOXP3highPD-L1neg | < 0.001 | 2.623 | 1.666 | 4.13 | 0.002* | 2.123 | 1.309 | 3.443 |
Middle | ||||||||
PD-L1 Pos vs Neg | 0.005 | 0.443 | 2.252 | 0.075 | 0.594 | 0.336 | 1.053 | |
CD8 High vs Low | 0.029 | 0.606 | 0.387 | 0.015* | 0.567 | 0.358 | 0.896 | |
Lower | ||||||||
PD-L1 Pos vs Neg | 0.003 | 0.55 | 0.37 | 0.819 | 0.522 | 0.869 | 0.566 | 1.334 |
CD8 High vs Low | 0.034 | 0.692 | 0.492 | 0.973 | 0.042* | 0.692 | 0.485 | 0.987 |
Tub | ||||||||
CD163 High vs Low | 0.040 | 1.647 | 1.022 | 2.653 | 0.026* | 1.765 | 1.071 | 2.908 |
PD-L1 Pos vs Neg | 0.002 | 0.462 | 0.281 | 0.759 | ||||
FOXP3highPD-L1neg | 0.014 | 1.868 | 1.137 | 3.070 | 0.227 | 1.387 | 0.815 | 2.316 |
Por | ||||||||
FOXP3 High vs Low | 0.018 | 1.442 | 1.065 | 1.951 | 0.949 | 0.988 | 0.691 | 1.414 |
CD163 High vs Low | 0.015 | 1.462 | 1.075 | 1.989 | 0.277 | 1.215 | 0.855 | 1.724 |
CD3 High vs Low | 0.002 | 0.617 | 0.458 | 0.832 | 0.246 | 0.814 | 0.574 | 1.153 |
CD8 High vs Low | 0.01 | 0.677 | 0.502 | 0.913 | 0.499 | 0.883 | 0.617 | 1.266 |
Sig+Muc | ||||||||
FOXP3highCD163high | 0.029 | 0.206 | 0.05 | 0.852 | 0.011* | 0.154 | 0.036 | 0.656 |
“a+b+c” | ||||||||
FOXP3lowCD163low | 0.001 | 0.319 | 0.161 | 0.634 | 0.001* | 0.319 | 0.161 | 0.634 |
“a+b” | ||||||||
FOXP3 High vs Low | 0.006 | 0.502 | 0.308 | 0.818 | 0.022* | 0.563 | 0.344 | 0.92 |
CD8 High vs Low | 0.003 | 0.506 | 0.323 | 0.793 | 0.006* | 0.533 | 0.34 | 0.837 |