Fig. 2

The characteristics of KIRC-related gene-directed network (KIRCD network) and identification of core clusters. a The global KIRCD network. b The number of diverse genes. c1–c3) The bar plots show the comparison of topological characteristics between KIRCD and IIKND. d The first pie chart shows the percent of significantly correlated interactions. The second pie chart shows the percent of positive and negative correlated interactions. e The density distribution curve of PCC values in the KIRCD network. f1–f5) The five core modules identified from the KIRCD network