Fig. 1
From: Reduced eIF3d accelerates HIV disease progression by attenuating CD8+ T cell function
The expression levels of eIF3d in PBMCs of EHI patients were reduced and negatively correlated with disease progression. a The expression levels of eIF3d mRNA in PBMCs of EHI patients and healthy controls (P = 0.001). b EIF3d was positively correlated with CD4+ T cell counts (P = 0.0003). c EIF3d was negatively correlated with viral loads (P = 0.0001). d Based on the median of eIF3d, EHI patients were divided into high- and low-expression groups. CD4+ T cell counts < 350 cells/μl were considered as the end point of follow-up in Kaplan–Meier survival analysis. The mean time for CD4+ T cell counts to reach 350 cells/μl in low expressers was significantly shorter than that in high expressers (P = 0.0003, Fig. 1d)