Table 9 Lists the cardiovascular ADRs predicted by the machine learning RF and SMO models on uncharacterized drugs in SIDER
From: Computational models for the prediction of adverse cardiovascular drug reactions
Drug name | ADR predicted by RF and SMO |
|---|---|
DB00176 Fluvoxamine | Decompensation cardiac |
DB00255 Diethylstilboestrol | Shock, cardiac failure congestive, cardiopulmonary failure, left ventricular failure, cor pulmonale, tachycardia |
DB00358 Mefloquine | Tachycardia, cardiac failure congestive |
DB00755 Tretinoin | Block heart, cardiac murmur, heart rate irregular, cardiac failure acute |
DB00882 Clomifene | Decompensation cardiac |
DB00927 Famotidine | Tachycardia, cardiac murmur, heart rate irregular, cardiac failure acute |
DB01026 Ketoconazole | Tachycardia, shock, cardiac failure congestive, cardiotoxicity, cor pulmonale, left ventricular failure, heart malformation, cardiopulmonary failure |
DB01394 Colchicine | Tachycardia, shock, cardiac failure congestive, cardiac murmur, cardiac disorder |
DB03904 Urea | Cardiac murmur, heart rate irregular, cardiac failure acute |
DB05260 Gallium nitrate | Decompensation cardiac |
DB06210 Eltrombopag | Block heart, cardiac murmur, heart rate irregular, cardiac failure acute, cardiac failure, arrhythmia |
DB08872 Gabapentin Enacarbil | Decompensation cardiac |