Table 2 Provides a comparison of the number of drugs and types of features used in the present study and for other ADR prediction studies
From: Computational models for the prediction of adverse cardiovascular drug reactions
Dataset | Drugs | Side effects | Substructures | Targets | Transporters | Enzymes | Pathways | Indications |
|---|---|---|---|---|---|---|---|---|
Pauwels et al. 2011 | 888 | 1385 | 881 | NA | NA | NA | NA | NA |
Wang et al. 2014 | 799 | 1385 | 881 | 775 | NA | NA | NA | 719 |
Zhang et al. 2015 | 569 | 4192 | NA | NA | NA | NA | NA | NA |
Kuang et al. 2014 | 404 | 461 | NA | NA | NA | NA | NA | NA |
Huang et al. 2011 | 578 | 1447 | NA | 3880 | NA | NA | NA | NA |
Zhang et al. 2015 | 1080 | 2260 | 881 | 1046 | 96 | 160 | 268 | 2537 |
Liu et al. 2013 | 832 | 1384 | 881 | 786 | 72 | 111 | 173 | 869 |
Present study | 965 | 5497 | 881 | 1264 | 86 | 182 | NA | 1840 |