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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: TNF-α-induced Tim-3 expression marks the dysfunction of infiltrating natural killer cells in human esophageal cancer

Fig. 2

Tim-3 expression is associated with apoptosis of tumor-infiltrating NK cells. a Correlation analysis between Tim-3+ NK cells and total NK cells in PBMC and TIL from esophageal cancer patients. b TIL were stained with antibodies to CD3, CD56, Tim-3 and Annexin V. The flow data are representative of 23 patients with esophageal cancer (left panel) and the results are shown as bar graphs (right panel). c NK cells in PBMC and TIL were examined for Annexin V binding, respectively. The flow data are representative of 14 patients with esophageal cancer (left panel) and the results are shown as bar graphs (right panel). ***p < 0.001; ns, not significant

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