From: ARL3 is downregulated and acts as a prognostic biomarker in glioma
Variables | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
P value | HR | 95% CI | P value | HR | 95% CI | |
ARL3 level | < 0.0001 | 0.873 | 0.845–0.901 | 0.0095 | 0.949 | 0.913–0.987 |
Gender | ||||||
 Male | Reference |  |  | Reference |  |  |
 Female | 0.345 | 0.847 | 0.60–1.195 | 0.7251 | 0.951 | 0.717–1.261 |
Age | < 0.0001 | 1.038 | 1.023–1.054 | 0.7727 | 1.002 | 0.987–1.018 |
WHO grade | ||||||
 Grade II | Reference |  |  | Reference |  |  |
 Grade III | < 0.0001 | 5.862 | 3.185–10.79 | < 0.0001 | 4.508 | 2.395–8.486 |
 Grade IV | < 0.0001 | 14.707 | 8.276–26.13 | < 0.0001 | 8.658 | 4.578–16.377 |
IDH status | ||||||
 Wild type | Reference |  |  | Reference |  |  |
 Mutant | < 0.0001 | 0.244 | 0.17–0.35 | 0.1475 | 0.705 | 0.439–1.132 |