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Table 2 Univariate analysis and multivariate analysis of overall survival in the primary cohort (CGGA)

From: ARL3 is downregulated and acts as a prognostic biomarker in glioma

Variables Univariate analysis Multivariate analysis
P value HR 95% CI P value HR 95% CI
ARL3 level < 0.0001 0.873 0.845–0.901 0.0095 0.949 0.913–0.987
Gender
 Male Reference    Reference   
 Female 0.345 0.847 0.60–1.195 0.7251 0.951 0.717–1.261
Age < 0.0001 1.038 1.023–1.054 0.7727 1.002 0.987–1.018
WHO grade
 Grade II Reference    Reference   
 Grade III < 0.0001 5.862 3.185–10.79 < 0.0001 4.508 2.395–8.486
 Grade IV < 0.0001 14.707 8.276–26.13 < 0.0001 8.658 4.578–16.377
IDH status
 Wild type Reference    Reference   
 Mutant < 0.0001 0.244 0.17–0.35 0.1475 0.705 0.439–1.132