Journal of Translational Medicine

Table 2 Spearman’s correlation coefficients (r) of clinical TNM stage, Ki 67 and with combined IVIM and non-Gaussian diffusion parameters

From: The volumetric-tumour histogram-based analysis of intravoxel incoherent motion and non-Gaussian diffusion MRI: association with prognostic factors in HER2-positive breast cancer

	ADC		Dt		f		D*		MK		MD
	cTNM	Ki67	cTNM	Ki67	cTNM	Ki67	cTNM	Ki67	cTNM	Ki67	cTNM	Ki67
50th	− 0.61	− 0.23*	− 0.04	− 0.11	0.04	0.22*	− 0.14	− 0.06	0.02	0.14	− 0.05	− 0.60
5th	− 0.23	− 0.14	− 0.02	− 0.08	0.04	0.13	− 0.04	0.01	0.05	0.18*	− 0.02	− 0.13
95th	− 0.40	− 0.24*	− 0.07	− 0.21*	0.04	0.20*	− 0.12	− 0.01	0.03	0.07	− 0.10	− 0.05
Skewness	0.28*	0.11	0.12	0.16	− 0.02	− 0.20*	0.05	− 0.01	− 0.12	− 0.07	0.16	− 0.04
Kurtosis	0.21*	0.19*	0.04	0.09	− 0.01	− 0.25*	0.09	− 0.02	− 0.12	− 0.13	0.06	− 0.01
Contrast	− 0.13	− 0.12	− 0.12	− 0.03	− 0.02	0.23*	− 0.10	− 0.02	0.01	0.12	− 0.01	0.12
Entropy	− 0.14	− 0.13	− 0.01	− 0.04	0.113	0.06	− 0.02	0.21	0.024	0.11	0.05	− 0.12

ADC apparent diffusion coefficient, Dt true diffusion coefficient, f perfusion fraction diffusion, D* pseudo-diffusion coefficient, MK mean kurtosis, MD mean diffusivity
*p < 0.05 was considered statistically significant

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ISSN: 1479-5876

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