Fig. 1

APOA-1 and AIBP expression in normal and neoplastic intestinal tissues. a IHC staining for AIBP and APOA-I in normal intestinal tissues, small intestinal adenoma, large tumors and colon tumors in C57BL/6 J-Apc^Min/+ mice; scale bar, 50 μm. b Western blot for APOA-1 and AIBP in intestinal normal, adenoma and tumor tissues in C57BL/6 J-Apc^Min/+ mice. c AIBP or APOA-I mRNA expression in the patients’ normal and cancerous tissues was evaluated according to the tumor differentiation stage (n = 47; *P < 0.05; **P < 0.01; ***P < 0.0001). d Staining for AIBP and APOA-I in human normal and malignant colon tissues from patients; scale bar, 50 μm. e, f qPCR and western blot results showing AIBP or APOA-I mRNA expression in various cell lines, including normal and colon cancer cell lines with a varying degree of malignancy. N, normal epithelial cells; L, low-malignant colon cancer cells; H, high-malignant colon cancer cells (NS, no significant difference; *P < 0.05; **P < 0.01)