Fig. 2

Differential gene expression in chronic fatigue syndrome (CFS) patients, Q fever fatigue syndrome (QFS) patients, and asymptomatic Q fever seropositive controls, compared to healthy controls, and QFS patients compared to CFS patients and Q fever seropositive controls. Heatmaps showing differential expression of down- and upregulated genes in circulating monocytes with a cut-off P value ≤ 10 × 10⁻⁵. Down- and upregulated genes in CFS patients (n = 10), QFS patients (n = 10), and asymptomatic Q fever seropositive controls (n = 10), compared to healthy controls (n = 10), down- and up-regulated genes in QFS patients (n = 10) compared to CFS patients (n = 10), and down- and upregulated genes in QFS patients (n = 10) compared to asymptomatic Q fever seropositive controls (n = 10). Heatmaps are based on level of differential expression, measured with log 2 fold change and depicted next to each gene, compared to various control groups. CFS chronic fatigue syndrome, QFS Q fever fatigue syndrome, QS asymptomatic Q fever seropositive controls