Table 1 Baseline characteristics and risk factors in derivation and validation cohorts
From: Development and validation of a risk prediction score for severe acute pancreatitis
Variable | Derivation cohort (n = 700) | Validation cohort (n = 194) |
|---|---|---|
Age, years (IQR) | 48 (37–63) | 49 (38–61) |
Male sex, N (%) | 435 (62.1) | 127 (65.5) |
Duration of symptoms, days | 1.83 ± 0.79 | 1.67 ± 0.78 |
SIRS, N (%) | 272 (38.9) | 82 (42.3) |
Etiology | ||
 Biliary, N (%) | 299 (42.7) | 74 (38.1) |
 Alcohol, N (%) | 96 (13.7) | 12 (6.2) |
 Hypertriglyceridemia, N (%) | 37 (5.3) | 31 (16.0) |
 Idiopathic, N (%) | 246 (35.1) | 73 (37.6) |
 Other, N (%) | 22 (3.1) | 4 (2) |
Laboratory findings | ||
 Hematocrit | 0.42 (0.38–0.46) | 0.43 (0.39–0.46) |
 Platelets (109/L) | 197 (158–233) | 206 (169–248) |
 Prothrombin time, s (IQR) | 13.8 (13.1–14.6) | 13.7 (13.2–14.5) |
 Albumin, g/L (IQR) | 36.2 (32.9–39.7) | 36.6 (32.7–39.7) |
 Bilirubin, mg/dL (IQR) | 1.16 (0.79–1.81) | 1.11 (0.76–1.75) |
 ALT, U/L (IQR) | 40 (19–107) | 33 (18–91) |
 AST, U/L (IQR) | 36 (21–85) | 33 (23–73) |
 Glucose, mg/dL (IQR) | 144 (117–193) | 139 (112–191) |
 BUN, mg/dL (IQR) | 13.4 (10.4–17.4) | 14.0 (10.6–17.9) |
Pleural effusion, N (%) | 135 (19.4) | 83 (42.8) |
Clinical outcomes | ||
 Patients with SAP, N (%) | 68 (9.7) | 18 (9.3) |
 Number of POF, N (%) | ||
  One organ failure | 38/68 (55.9) | 7/18 (38.9) |
  Two organ failure | 19/68 (27.9) | 6/18 (33.3) |
  Three organ failure | 11/68 (16.2) | 5/18 (27.8) |
 Type of POF | ||
  Respiratory failure, N (%) | 56/68 (82.4) | 16/18 (88.9) |
  Renal failure, N (%) | 24/68 (35.3) | 10/18 (55.6) |
  Cardiovascular failure, N (%) | 29/68 (42.7) | 8/18 (44.4) |
Length of hospital stay, days (IQR) | 10 (7–9) | 11 (7–17) |
 Hospital mortality, N (%) | 11 (1.6) | 2 (1.0) |