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Table 5 Disease-specific profiles of elevated twofold lipid elements of patients with severe acute pneumonia (SAP), acute pulmonary embolism (APE), or acute exacerbation of chronic pulmonary diseases (AECPD) with statistical significance, as compared with healthy control (p < 0.05 or less)

From: Values of integration between lipidomics and clinical phenomes in patients with acute lung infection, pulmonary embolism, or acute exacerbation of chronic pulmonary diseases: a preliminary study

SAP

APE

AECPD

Elements

Folds

pvalue

Elements

Folds

pvalue

Elements

Folds

pvalue

Elevated twofold lipid elements

 d181So

21.71

0.04

PC 16:0/26:0

3.98

0.02

lysoPI 22:4 (sn-1)

5.55

0.03

 lysoPS17:1

8.70

0.03

lysoPS16:1

3.09

0.01

lysoPS22:6

3.28

0.05

 lysoPE 22:6 (sn-1)

5.99

0.05

lysoPS17:0

3.01

0.01

lysoPC 17:1 (sn-1)

3.24

0.04

 lysoPG14:0

5.90

0.01

lysoPC 22:6 (sn-1)

2.56

0.01

lysoPI 20:0 (sn-1)

2.80

0.03

 lysoPS16:0

5.44

0.01

lysoPC 19:0 (sn-1)

2.50

0.01

lysoPS20:4

2.71

0.03

 PS32:0

4.43

0.03

lysoPC 20:3 (sn-1)

2.48

0.02

lysoPG15:0

2.46

0.04

 PS32:1

4.07

0.01

lysoPC 20:5 (sn-1)

2.40

0.01

PS37:5

2.10

0.01

 lysoPI 20:2 (sn-1)

4.02

0.02

PC 39:0

2.36

0.00

PG36:2

2.08

0.01

 lysoPS14:0

3.64

0.02

lysoPC 18:0 (sn-1)

2.33

0.01

   

 lysoPI 19:0 (sn-1)

3.52

0.00

lysoPC 20:4 (sn-1)

2.31

0.01

   

 PC 39:2

3.45

0.02

lysoPC 18:3 (sn-1)

2.30

0.03

   

 lysoPS18:3

3.32

0.01

PS36:6

2.27

0.04

   

 PS34:2

2.94

0.01

lysoPC 20:2 (sn-1)

2.26

0.03

   

 PE 42:7

2.92

0.04

lysoPC 17:0 (sn-1)

2.22

0.01

   

 PE 37:3

2.66

0.05

lysoPC 20:0 (sn-1)

2.20

0.03

   

 PC 37:4

2.44

0.02

lysoPS20:5

2.20

0.03

   

 PE 35:1

2.26

0.04

PS38:7

2.18

0.01

   

 PS33:2

2.23

0.04

PC 40:7

2.17

0.00

   

 PS35:2

2.23

0.01

lysoPC 15:0 (sn-2)

2.12

0.04

   

 PE 39:6

2.11

0.02

lysoPC 16:0 (sn-2)

2.12

0.01

   

 lysoPG18:3

2.08

0.04

PS33:0

2.11

0.02

   

 PC 40:5

2.06

0.00

lysoPC 18:1 (sn-1)

2.05

0.02

   

 PC 40:8

2.01

0.03

      

Declined twofold lipid elements

 PA 18:1/20:4

0.25

0.04

PA 14:0/24:5

0.18

0.04

PA 10:0/18:0

0.43

0.00

 PG40:5

0.47

0.03

PA 18:0/20:5

0.35

0.02

PA 10:0/18:1

0.44

0.02

 PG40:6

0.33

0.00

PS38:1

0.39

0.02

PA 16:1/18:4

0.33

0.03

 PG40:8

0.31

0.00

PS40:1

0.32

0.04

PS 18:0/22:3

0.46

0.01

 PI 18:0/17:1

0.39

0.00

   

PS 20:3/22:6

0.45

0.02