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Table 2 Association between office systolic BP, metabolic parameters and gene expression at 5 years of age estimated by multiple regression analysis

From: Blood cell transcript levels in 5-year-old children as potential markers of breastfeeding effects in those small for gestational age at birth

Variable Beta P value
Systolic blood pressure
 CPTL1 0.161 0.473
 FASN 0.133 0.578
 FTO 0.199 0.398
 INSR − 0.534 0.018
 LEPR − 0.128 0.578
 MC4R − 0.031 0.903
 UCP2 − 0.003 0.989
 R2: 0.279   
Uric acid
 CPTL1 0.393 0.138
 FASN − 0.109 0.690
 FTO − 0.128 0.558
 INSR − 0.026 0.910
 LEPR − 0.096 0.692
 MC4R − 0.122 0.668
 UCP2 − 0.546 0.031
 R2: 0.38   
HDL cholesterol
 CPTL1 0.409 0.071
 FASN − 0.534 0.022
 FTO 0.590 0.007
 INSR 0.126 0.525
 LEPR 0.152 0.476
 UCP2 0.121 0.559
 MC4R 0.176 0.474
 R2: 0.49   
Insulin
 CPTL1 − 0.115 0.598
 FASN 0.672 0.011
 FTO − 0.170 0.451
 INSR − 0.414 0.062
 LEPR − 0.086 0.689
 MC4R 0.126 0.605
 UCP2 0.205 0.381
 R2: 0.337   
  1. Data with significant P value (< 0.05) are indicated in italic
  2. CPT1A, carnitine palmitoyl transferase 1 alpha; FASN, fatty acid synthase; FTO, alpha-Ketoglutarate dependent dioxygenase; INSR, insulin receptor; LEPR, Leptin receptor, long-form; MC4R, Melanocortin 4 receptor, UCP2, Uncoupling protein 2
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Journal of Translational Medicine

ISSN: 1479-5876

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