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Table 2 Association between office systolic BP, metabolic parameters and gene expression at 5 years of age estimated by multiple regression analysis

From: Blood cell transcript levels in 5-year-old children as potential markers of breastfeeding effects in those small for gestational age at birth

Variable

Beta

P value

Systolic blood pressure

 CPTL1

0.161

0.473

 FASN

0.133

0.578

 FTO

0.199

0.398

 INSR

− 0.534

0.018

 LEPR

− 0.128

0.578

 MC4R

− 0.031

0.903

 UCP2

− 0.003

0.989

 R2: 0.279

  

Uric acid

 CPTL1

0.393

0.138

 FASN

− 0.109

0.690

 FTO

− 0.128

0.558

 INSR

− 0.026

0.910

 LEPR

− 0.096

0.692

 MC4R

− 0.122

0.668

 UCP2

− 0.546

0.031

 R2: 0.38

  

HDL cholesterol

 CPTL1

0.409

0.071

 FASN

− 0.534

0.022

 FTO

0.590

0.007

 INSR

0.126

0.525

 LEPR

0.152

0.476

 UCP2

0.121

0.559

 MC4R

0.176

0.474

 R2: 0.49

  

Insulin

 CPTL1

− 0.115

0.598

 FASN

0.672

0.011

 FTO

− 0.170

0.451

 INSR

− 0.414

0.062

 LEPR

− 0.086

0.689

 MC4R

0.126

0.605

 UCP2

0.205

0.381

 R2: 0.337

  
  1. Data with significant P value (< 0.05) are indicated in italic
  2. CPT1A, carnitine palmitoyl transferase 1 alpha; FASN, fatty acid synthase; FTO, alpha-Ketoglutarate dependent dioxygenase; INSR, insulin receptor; LEPR, Leptin receptor, long-form; MC4R, Melanocortin 4 receptor, UCP2, Uncoupling protein 2
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Journal of Translational Medicine

ISSN: 1479-5876

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