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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Fibroblast growth factor 23, endothelium biomarkers and acute kidney injury in critically-ill patients

Fig. 3

Mediation analyses of the association between FGF23 and severe AKI. Path models and mediation analyses describe mediation of the association between FGF23 and severe AKI through endothelial-related biomarkers individually. Path effects are reported as Odds-ratio scale of natural log-transformed values of biomarkers. Models are adjusted for age, gender, Charlson comorbidity index, BMI greater than 30 kg/m2, surgical admission, use of vasoactive drugs, need for mechanical ventilation, use of nephrotoxic drugs and APACHE II score at ICU admission. Residual direct effects are labeled as path A in each model, and indirect effects are labeled as letters B and C

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