Table 2 Univariate and multivariate models for chemotherapy-free survival in gastric cancer patients who underwent chemotherapy in The Cancer Genome Atlas (TCGA)
Characteristic | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
Chemotherapy-free survival | ||||
 DNAH status | 0.456 (0.248–0.848) | 0.011 | 0.446 (0.233–0.856) | 0.015 |
 TNM stage | 1.767 (1.010–3.092) | 0.046 | 1.275 (0.716–2.268) | 0.409 |
 R0 resection | 5.780 (2.464–13.558) | < 0.001 | 5.289 (2.097–13.341) | < 0.001 |
 Grade | 1.327 (0.722–2.439) | 0.361 |  |  |
 Age at diagnosis, y | 1.010 (0.982–1.308) | 0.482 |  |  |
Fluoropyrimidine-free survival | ||||
 DNAH status | 0.518 (0.264–0.014) | 0.055 |  |  |
 TNM stage | 1.485 (1.189–5.192) | 0.016 | 2.080 (0.961–4.502) | 0.063 |
 R0 resection | 6.295 (2.338–16.963) | < 0.001 | 5.136 (1.848–14.275) | 0.002 |
 Grade | 1.429 (0.794–2.575) | 0.234 |  |  |
 Age at diagnosis, y | 1.019 (0.986–1.053) | 0.269 |  |  |
Platinum-free survival | ||||
 DNAH status | 0.217 (0.061–0.768) | 0.018 | 0.137 (0.030–0.629) | 0.011 |
 TNM stage | 1.716 (0.761–3.872) | 0.193 |  |  |
 R0 resection | 4.184 (1.172–14.932) | 0.027 | 5.116 (1.415–18.501) | 0.013 |
 Grade | 1.415 (0.454–4.411) | 0.550 |  |  |
 Age at diagnosis, y | 1.000 (0.959–1.044) | 0.988 |  |  |