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Table 3 Gene lists for gene set signatures

From: Combinations of immuno-checkpoint inhibitors predictive biomarkers only marginally improve their individual accuracy

IFN-y (reduced set)
CXCL10, CXCL9, HLA-DRA, IDO1, IFNG, STAT1
IFN-y (expanded set)
CCL5, CD2, CD3D, CD3E, CIITA, CXCL10, CXCL13, CXCR6, GZMB, GZMK, HLA-DRA, HLA-E, IDO1, IL2RG, LAG3, NKG7, STAT1, TAGAP
ImmunoPhenoScore (IPS)
ACAP1, ADRM1, AHSA1, AIM2, APOL3, ARHGAP10, ATM, ATP10D, B2 M, BIRC3, BRIP1, C1GALT1C1, C3AR1, CASP3, CASQ1, CCL20, CCL3L1, CCL4, CCL5, CCNB1, CCR2, CCR5, CCR7, CCT6B, CD14, CD160, CD2, CD27, CD274, CD300E, CD37, CD3D, CD3E, CD3G, CD55, CD69, CD72, CD86, CD8A, CETN3, CFLAR, CLEC5A, CMKLR1, CSE1L, CTLA4, CXCR4, DAPP1, DARS, DOCK9, DUSP2, ESCO2, ETS1, EXO1, EXOC6, EXOSC9, EZH2, FCGR2A, FCGR2B, FCGR3A, FCRL6, FERMT3, FLT3LG, FOXP3, GDE1, GEMIN6, GNLY, GPSM3, GPT2, GZMA, GZMH, GZMK, GZMM, HAPLN3, HAVCR2, HLA-A, HLA-B, HLA-C, HLA-DMB, HLA-DPA1, HLA-DPA1, HLA-DPB1, HLA-DPB1, HLA-E, HLA-F, IARS, ICOS, IDO1, IFI16, IL18BP, IL2RB, IL34, IL4R, ITGA4, ITGAL, ITGAM, KIF11, KNTC1, L1CAM, LAG3, LCK, LIME1, LIPA, LRP1, LRRC42, LTK, MARCO, MMP12, MNDA, MPZL1, MRC1, MS4A6A, NCOA4, NEFL, NFKBIA, NKG7, NUF2, PARVG, PDCD1, PDCD1LG2, PDGFRL, PELO, PIK3IP1, PLEK, PRC1, PRSS23, PSAP, PSAT1, PTGER2, PTGES2, PTGIR, PTGS1, PTRH2, REPS1, RGS1, RTKN2, S100A8, S100A9, SAMSN1, SCG2, SDPR, SELL, SETD7, SIGLEC14, SIGLEC6, SIK1, ST8SIA4, STAB 1, TAL1, TAP1, TAP2, TFEC, TIGIT, TIMM13, TIPIN, TPK1, TRAT1, TRIB2, UQCRB, USP9Y, WIPF1, ZAP70, ZCRB1
ICB resistance signature 1
ADAMTS7, AXL, COL12A1, COL8A1, FAP, FBLN1, INHBA, LOXL2, MMP1, MMP13, ROR2, TAGLN, TWIST2, WNT5A
ICB resistance signature 2
CNN1, COL3A1, MXRA7, SERPINF2
ICB resistance signature 3
CST2, LAMA3
AXL pathway
AXL, FLT1, FLT4, GAS6, KDR, MERTK, MET, RET, TEK, TYRO3
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