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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Compound α-keto acid tablet supplementation alleviates chronic kidney disease progression via inhibition of the NF-kB and MAPK pathways

Fig. 7

The effect of KA on renal survival probability in CKD patients at different stage. The probability to reach the end-point was lower in KA group than no-KA group at CKD stages 4 and 5 when adjusted in a log rank test (p = 0.0241). For patients at stage 3 to 5, KA also showed a protective effect on renal function before 30 months, after 30 months, patients in KA group presented a deteriorate renal situation. For patients at stage 3, the incidence of end-point (n = 0.035, 7/201) in KA group was lower than no-KA group, however, the whole incidence of end-point was rather less than at stage 4 and 5 (n = 0.107, 13/12)

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